Gene description for Ehd2
Gene name EH-domain containing 2
Gene symbol Ehd2
Other names/aliases MGEPS
Species Rattus norvegicus
 Database cross references - Ehd2
ExoCarta ExoCarta_361512
Entrez Gene 361512
UniProt Q4V8H8  
 Ehd2 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Ehd2
Molecular Function
    protein domain specific binding GO:0019904 ISO
    GTP binding GO:0005525 IEA
    hydrolase activity GO:0016787 IEA
    ATP binding GO:0005524 IEA
    calcium ion binding GO:0005509 IEA
Biological Process
    protein localization to plasma membrane GO:0072659 ISS
    positive regulation of endocytic recycling GO:2001137 ISS
    cortical actin cytoskeleton organization GO:0030866 ISO
    metabolic process GO:0008152 IEA
    endocytic recycling GO:0032456 ISS
    endocytosis GO:0006897 ISO
    positive regulation of myoblast fusion GO:1901741 ISS
Subcellular Localization
    perinuclear region of cytoplasm GO:0048471 ISO
    plasma membrane GO:0005886 ISS
    recycling endosome membrane GO:0055038 ISS
    membrane GO:0016020 ISO
    extracellular exosome GO:0070062 ISO
    caveola GO:0005901 ISO
 Experiment description of studies that identified Ehd2 in exosomes
Experiment ID 225
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Ehd2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Picalm 89816
Reconstituted Complex Rattus norvegicus
2 Slc2a4 25139
Affinity Capture-Western Rattus norvegicus
View the network image/svg+xml
 Pathways in which Ehd2 is involved
Factors involved in megakaryocyte development and platelet production IEA Reactome

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