Gene description for NINJ1
Gene name ninjurin 1
Gene symbol NINJ1
Other names/aliases NIN1
NINJURIN
Species Homo sapiens
 Database cross references - NINJ1
ExoCarta ExoCarta_4814
Entrez Gene 4814
HGNC 7824
MIM 602062
UniProt Q92982  
 NINJ1 identified in exosomes derived from the following tissue/cell type
Prostate cancer cells 25844599    
 Gene ontology annotations for NINJ1
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    positive regulation of cell-matrix adhesion GO:0001954 IEA
    tissue regeneration GO:0042246 IEA
    cell adhesion GO:0007155 IEA
    hyaloid vascular plexus regression GO:1990384 IEA
    nervous system development GO:0007399 TAS
Subcellular Localization
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified NINJ1 in exosomes
1
Experiment ID 275
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|RAB5A
EV Cytosolic markers
CD9|CD82|CD63|CD81
EV Membrane markers
AIF
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T.
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
 Protein-protein interactions for NINJ1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which NINJ1 is involved
No pathways found





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