Gene description for SLC50A1
Gene name solute carrier family 50 (sugar efflux transporter), member 1
Gene symbol SLC50A1
Other names/aliases HsSWEET1
RAG1AP1
SCP
SWEET1
slv
Species Homo sapiens
 Database cross references - SLC50A1
ExoCarta ExoCarta_55974
Entrez Gene 55974
HGNC 30657
MIM 613683
UniProt Q9BRV3  
 SLC50A1 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for SLC50A1
Molecular Function
    glucoside transmembrane transporter activity GO:0042947 IDA
Biological Process
    carbohydrate transport GO:0008643 IEA
    DNA recombination GO:0006310 IEA
    glucoside transport GO:0042946 IDA
    positive regulation of gene expression, epigenetic GO:0045815 ISS
Subcellular Localization
    endomembrane system GO:0012505 ISS
    Golgi membrane GO:0000139 IEA
    integral component of membrane GO:0016021 IEA
    Golgi apparatus GO:0005794 IDA
    nucleus GO:0005634 IC
    plasma membrane GO:0005886 IDA
 Experiment description of studies that identified SLC50A1 in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for SLC50A1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SLC50A1 is involved
No pathways found





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