Gene description for Pgam2
Gene name phosphoglycerate mutase 2
Gene symbol Pgam2
Other names/aliases -
Species Mus musculus
 Database cross references - Pgam2
ExoCarta ExoCarta_56012
Vesiclepedia VP_56012
Entrez Gene 56012
UniProt O70250  
 Pgam2 identified in sEVs derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Pgam2
Molecular Function
    bisphosphoglycerate mutase activity GO:0004082 IEA
    phosphoglycerate mutase activity GO:0004619 IDA
    phosphoglycerate mutase activity GO:0004619 ISO
    protein binding GO:0005515 IPI
    hydrolase activity GO:0016787 IEA
    identical protein binding GO:0042802 IEA
    identical protein binding GO:0042802 ISO
    2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity GO:0046538 IEA
    2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity GO:0046538 ISO
Biological Process
    gluconeogenesis GO:0006094 IEA
    gluconeogenesis GO:0006094 ISO
    glycolytic process GO:0006096 IDA
    glycolytic process GO:0006096 ISO
    striated muscle contraction GO:0006941 IEA
    striated muscle contraction GO:0006941 ISO
    Notch signaling pathway GO:0007219 IDA
    spermatogenesis GO:0007283 IEA
    response to mercury ion GO:0046689 IEA
    response to mercury ion GO:0046689 ISO
    canonical glycolysis GO:0061621 IDA
Subcellular Localization
    cytosol GO:0005829 IDA
 Experiment description of studies that identified Pgam2 in sEVs
1
Experiment ID 210
MISEV standards
EM
Biophysical techniques
CD81|FLOT1
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors "Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL."
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Pgam2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Pvalb  
Co-fractionation Mus musculus
2 Tpi1 21991
Co-fractionation Mus musculus
3 HSD17B10 3028
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which Pgam2 is involved
PathwayEvidenceSource
Gluconeogenesis IEA Reactome
Glucose metabolism IEA Reactome
Glycolysis IEA Reactome
Metabolism IEA Reactome
Metabolism of carbohydrates IEA Reactome





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