Gene description for Ube2d2a
Gene name ubiquitin-conjugating enzyme E2D 2A
Gene symbol Ube2d2a
Other names/aliases 1500034D03Rik
Ubc2e
Ube2d2
ubc4
Species Mus musculus
 Database cross references - Ube2d2a
ExoCarta ExoCarta_56550
Entrez Gene 56550
UniProt P62838  
 Ube2d2a identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Ube2d2a
Molecular Function
    ATP binding GO:0005524 IEA
    ligase activity GO:0016874 IEA
    ubiquitin conjugating enzyme activity GO:0061631 ISO
    nucleotide binding GO:0000166 IEA
    ubiquitin-protein transferase activity GO:0004842 ISO
    protein binding GO:0005515 IPI
Biological Process
    protein ubiquitination GO:0016567 ISO
    protein polyubiquitination GO:0000209 ISO
    protein K48-linked ubiquitination GO:0070936 ISO
    protein autoubiquitination GO:0051865 ISO
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    ubiquitin ligase complex GO:0000151 ISO
    protein complex GO:0043234 ISO
 Experiment description of studies that identified Ube2d2a in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Ube2d2a
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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