Gene description for Ube2v1
Gene name ubiquitin-conjugating enzyme E2 variant 1
Gene symbol Ube2v1
Other names/aliases 0610011J09Rik
AI256840
CROC-1
CROC1
D7Bwg1382e
UEV-1
Species Mus musculus
 Database cross references - Ube2v1
ExoCarta ExoCarta_66589
Entrez Gene 66589
UniProt Q9CZY3  
 Ube2v1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Ube2v1
Molecular Function
    protein binding GO:0005515 IPI
    ubiquitin conjugating enzyme activity GO:0061631 IGI
    ubiquitin protein ligase activity GO:0061630 IBA
    ubiquitin conjugating enzyme binding GO:0031624 IPI
    ubiquitin protein ligase binding GO:0031625 IBA
Biological Process
    protein K63-linked ubiquitination GO:0070534 ISO
    positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 ISO
    error-free postreplication DNA repair GO:0042275 IGI
    positive regulation of NF-kappaB transcription factor activity GO:0051092 ISO
Subcellular Localization
    ubiquitin ligase complex GO:0000151 ISO
    ubiquitin conjugating enzyme complex GO:0031371 ISO
    UBC13-UEV1A complex GO:0035370 ISO
    extracellular exosome GO:0070062 ISO
    protein complex GO:0043234 ISO
    cytoplasm GO:0005737 ISO
    nucleus GO:0005634 IBA
 Experiment description of studies that identified Ube2v1 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Ube2v1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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