Gene description for Cand1
Gene name cullin associated and neddylation disassociated 1
Gene symbol Cand1
Other names/aliases 2310038O07Rik
6330512O03Rik
AI195005
AI846556
D10Ertd516e
Tp120a
mKIAA0829
Species Mus musculus
 Database cross references - Cand1
ExoCarta ExoCarta_71902
Entrez Gene 71902
UniProt Q6ZQ38  
 Cand1 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Cand1
Molecular Function
    protein binding GO:0005515 IPI
    TBP-class protein binding GO:0017025 ISO
Biological Process
    cell differentiation GO:0030154 ISO
    negative regulation of catalytic activity GO:0043086 ISO
    positive regulation of RNA polymerase II transcriptional preinitiation complex assembly GO:0045899 ISO
    SCF complex assembly GO:0010265 ISO
    positive regulation of transcription, DNA-templated GO:0045893 ISO
    protein ubiquitination GO:0016567 ISO
Subcellular Localization
    cytoplasm GO:0005737 ISO
    membrane GO:0016020 ISO
    ubiquitin ligase complex GO:0000151 ISO
    nucleoplasm GO:0005654 ISO
    nucleus GO:0005634 ISO
    cullin-RING ubiquitin ligase complex GO:0031461 ISO
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Cand1 in exosomes
1
Experiment ID 210
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD81|FLOT1
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Cand1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Cand1 is involved
No pathways found





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