Gene description for Zfp276
Gene name zinc finger protein (C2H2 type) 276
Gene symbol Zfp276
Other names/aliases AW048709
D8Ertd370e
D8Ertd377e
Znf276
Species Mus musculus
 Database cross references - Zfp276
ExoCarta ExoCarta_57247
Vesiclepedia VP_57247
Entrez Gene 57247
UniProt Q8CE64  
 Zfp276 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Zfp276
Molecular Function
    zinc ion binding GO:0008270 IEA
    chromatin insulator sequence binding GO:0043035 IBA
    sequence-specific double-stranded DNA binding GO:1990837 IEA
    sequence-specific double-stranded DNA binding GO:1990837 ISO
Biological Process
    regulation of transcription by RNA polymerase II GO:0006357 IBA
Subcellular Localization
    kinetochore GO:0000776 IBA
    kinetochore GO:0000776 ISO
    kinetochore GO:0000776 ISS
    nucleus GO:0005634 IEA
    chromosome GO:0005694 IBA
 Experiment description of studies that identified Zfp276 in exosomes
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Zfp276
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Lrwd1  
Co-fractionation Mus musculus
2 Trappc12  
Co-fractionation Mus musculus
3 Bub1b 12236
Co-fractionation Mus musculus
4 Mad1l1  
Co-fractionation Mus musculus
5 Meaf6  
Co-fractionation Mus musculus
6 Ckap5 75786
Co-fractionation Mus musculus
7 Bub1  
Co-fractionation Mus musculus
8 Cenpe  
Co-fractionation Mus musculus
9 Spag5  
Co-fractionation Mus musculus
10 Cenph  
Co-fractionation Mus musculus
11 Pafah1b1 18472
Co-fractionation Mus musculus
12 Nup85  
Co-fractionation Mus musculus
13 Seh1l 72124
Co-fractionation Mus musculus
14 Nfkb1  
Two-hybrid Mus musculus
15 Apc  
Co-fractionation Mus musculus
View the network image/svg+xml
 Pathways in which Zfp276 is involved
No pathways found





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