Gene description for Seh1l
Gene name SEH1-like (S. cerevisiae
Gene symbol Seh1l
Other names/aliases 2610007A16Rik
AW540070
SEC13L
SEH1A
SEH1B
Seh1
Species Mus musculus
 Database cross references - Seh1l
ExoCarta ExoCarta_72124
Entrez Gene 72124
UniProt Q8R2U0  
 Seh1l identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Seh1l
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    transport GO:0006810 IEA
    cytokine production involved in inflammatory response GO:0002534 IMP
    attachment of mitotic spindle microtubules to kinetochore GO:0051315 ISO
    nuclear pore organization GO:0006999 ISO
    mitotic metaphase plate congression GO:0007080 ISO
    mRNA transport GO:0051028 IEA
    cell division GO:0051301 IEA
    cell cycle GO:0007049 IEA
    defense response to Gram-positive bacterium GO:0050830 IMP
    protein transport GO:0015031 IEA
    mitotic nuclear division GO:0007067 IEA
    chromosome segregation GO:0007059 IEA
Subcellular Localization
    nuclear pore outer ring GO:0031080 ISO
    kinetochore GO:0000776 ISO
    chromosome, centromeric region GO:0000775 IEA
    chromosome GO:0005694 IEA
    nuclear pore GO:0005643 IEA
    nucleus GO:0005634 IEA
 Experiment description of studies that identified Seh1l in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Seh1l
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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