Gene description for SEPP1
Gene name selenoprotein P, plasma, 1
Gene symbol SEPP1
Other names/aliases SELP
SEPP
SeP
Species Homo sapiens
 Database cross references - SEPP1
ExoCarta ExoCarta_6414
Entrez Gene 6414
HGNC 10751
MIM 601484
UniProt P49908  
 SEPP1 identified in exosomes derived from the following tissue/cell type
Saliva 19199708    
 Gene ontology annotations for SEPP1
Molecular Function
    selenium binding GO:0008430 IEA
Biological Process
    growth GO:0040007 IEA
    selenium compound metabolic process GO:0001887 IEA
    sexual reproduction GO:0019953 IEA
    locomotory behavior GO:0007626 IEA
    post-embryonic development GO:0009791 IEA
    brain development GO:0007420 IEA
    response to oxidative stress GO:0006979 TAS
Subcellular Localization
    extracellular region GO:0005576 NAS
    extracellular space GO:0005615 IEA
    extracellular exosome GO:0070062 IDA
 Experiment description of studies that identified SEPP1 in exosomes
1
Experiment ID 66
ISEV standards
IEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
CD63|CD81
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for SEPP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SEPP1 is involved
No pathways found





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