Gene description for Zfand6
Gene name zinc finger, AN1-type domain 6
Gene symbol Zfand6
Other names/aliases 3110005P07Rik
Awp1
Za20d3
Species Mus musculus
 Database cross references - Zfand6
ExoCarta ExoCarta_65098
Entrez Gene 65098
UniProt Q9DCH6  
 Zfand6 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Zfand6
Molecular Function
    zinc ion binding GO:0008270 IEA
    DNA binding GO:0003677 IEA
    protein binding GO:0005515 IPI
    metal ion binding GO:0046872 IEA
    polyubiquitin binding GO:0031593 IDA
Biological Process
    negative regulation of apoptotic process GO:0043066 ISO
    signal transduction GO:0007165 IPI
    protein targeting to peroxisome GO:0006625 IDA
    transport GO:0006810 IEA
    regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 ISO
    cellular response to tumor necrosis factor GO:0071356 ISO
    protein transport GO:0015031 IEA
    apoptotic process GO:0006915 IEA
Subcellular Localization
    intracellular GO:0005622 IDA
    cell GO:0005623 IDA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified Zfand6 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Zfand6
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Zfand6 is involved
No pathways found





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