Gene description for Dnm2
Gene name	dynamin 2
Gene symbol	Dnm2
Other names/aliases	Dyn2 Udnm b2b2159Clo
Species	Mus musculus
Database cross references - Dnm2
ExoCarta	ExoCarta_13430
Entrez Gene	13430
UniProt	P39054
Dnm2 identified in exosomes derived from the following tissue/cell type
Macrophages	23658846
Macrophages	23658846
Macrophages	23658846

Gene ontology annotations for Dnm2

Molecular Function     hydrolase activity GO:0016787 IEA     GTP binding GO:0005525 IEA     protein binding GO:0005515 IPI     WW domain binding GO:0050699 ISO     nucleotide binding GO:0000166 IEA     phosphatidylinositol 3-kinase regulatory subunit binding GO:0036312 ISO     nitric-oxide synthase binding GO:0050998 ISO     GTPase activity GO:0003924 IEA     protein kinase binding GO:0019901 ISO     SH3 domain binding GO:0017124 ISO     protein complex binding GO:0032403 ISO     D2 dopamine receptor binding GO:0031749 ISO Biological Process     cilium morphogenesis GO:0060271 ISO     positive regulation of phagocytosis GO:0050766 ISO     transferrin transport GO:0033572 ISO     regulation of Golgi organization GO:1903358 ISO     macropinocytosis GO:0044351 ISO     regulation of Rac protein signal transduction GO:0035020 ISO     Golgi to plasma membrane transport GO:0006893 ISO     negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 ISO     positive regulation of substrate adhesion-dependent cell spreading GO:1900026 ISO     positive regulation of endocytosis GO:0045807 ISO     positive regulation of nitric oxide biosynthetic process GO:0045429 ISO     endocytosis GO:0006897 IEA     cellular response to dopamine GO:1903351 ISO     positive regulation of sodium:potassium-exchanging ATPase activity GO:1903408 ISO     receptor-mediated endocytosis GO:0006898 ISO     neuron projection morphogenesis GO:0048812 ISO     receptor internalization GO:0031623 ISO     negative regulation of membrane tubulation GO:1903526 ISO     regulation of axon extension GO:0030516 ISO     positive regulation of lamellipodium assembly GO:0010592 ISO     G-protein coupled receptor internalization GO:0002031 ISO Subcellular Localization     phagocytic cup GO:0001891 ISO     lamellipodium GO:0030027 ISO     clathrin-coated endocytic vesicle GO:0045334 ISO     membrane GO:0016020 IEA     extracellular exosome GO:0070062 ISO     nucleus GO:0005634 ISO     centrosome GO:0005813 ISO     protein complex GO:0043234 ISO     focal adhesion GO:0005925 ISO     synapse GO:0045202 IEA     cytoplasm GO:0005737 ISO     coated pit GO:0005905 ISO     cytosol GO:0005829 ISO     Golgi apparatus GO:0005794 ISO     trans-Golgi network GO:0005802 ISO     growth cone GO:0030426 ISO     perinuclear region of cytoplasm GO:0048471 ISO     endosome GO:0005768 ISO     plasma membrane GO:0005886 ISO     Golgi membrane GO:0000139 ISO     microtubule GO:0005874 ISO     postsynaptic membrane GO:0045211 ISO     photoreceptor inner segment GO:0001917 IDA     cell junction GO:0030054 ISO     ruffle membrane GO:0032587 ISO     cytoskeleton GO:0005856 IEA