Gene description for Dynlt3
Gene name dynein light chain Tctex-type 3
Gene symbol Dynlt3
Other names/aliases 2310075M16Rik
AU042796
Tcte1l
Species Mus musculus
 Database cross references - Dynlt3
ExoCarta ExoCarta_67117
Entrez Gene 67117
UniProt P56387  
 Dynlt3 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Dynlt3
Molecular Function
    motor activity GO:0003774 IEA
    identical protein binding GO:0042802 ISO
Biological Process
    cell division GO:0051301 IEA
    mitotic nuclear division GO:0007067 IEA
    regulation of mitotic cell cycle GO:0007346 ISO
    transport GO:0006810 IEA
    cell cycle GO:0007049 IEA
Subcellular Localization
    kinetochore GO:0000776 ISO
    chromosome, centromeric region GO:0000775 IEA
    cytoskeleton GO:0005856 IEA
    cytoplasmic dynein complex GO:0005868 ISO
    nucleus GO:0005634 IEA
    cytoplasm GO:0005737 ISO
    chromosome GO:0005694 IEA
    microtubule GO:0005874 IEA
    dynein complex GO:0030286 IEA
 Experiment description of studies that identified Dynlt3 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Dynlt3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Dynlt3 is involved
No pathways found





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