Gene description for Eef1g
Gene name eukaryotic translation elongation factor 1 gamma
Gene symbol Eef1g
Other names/aliases 2610301D06Rik
AA407312
EF1G
Species Mus musculus
 Database cross references - Eef1g
ExoCarta ExoCarta_67160
Vesiclepedia VP_67160
Entrez Gene 67160
UniProt Q9D8N0  
 Eef1g identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Eef1g
Molecular Function
    translation elongation factor activity GO:0003746 IEA
Biological Process
    translational elongation GO:0006414 IBA
    translational elongation GO:0006414 IEA
    response to virus GO:0009615 IEA
Subcellular Localization
    nucleus GO:0005634 IBA
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 ISO
    endoplasmic reticulum GO:0005783 IEA
    endoplasmic reticulum GO:0005783 ISO
 Experiment description of studies that identified Eef1g in sEVs
1
Experiment ID 907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Eef1g
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Kcna3  
Affinity Capture-MS Mus musculus
2 Kctd13  
Affinity Capture-MS Mus musculus
3 Rpl23 65019
Co-fractionation Mus musculus
4 Rpl24 68193
Co-fractionation Mus musculus
5 Tmem173  
Proximity Label-MS Mus musculus
6 Vars 22321
Co-fractionation Mus musculus
7 Rpl32 19951
Co-fractionation Mus musculus
8 Rpl6 19988
Co-fractionation Mus musculus
9 Eed  
Affinity Capture-MS Mus musculus
10 Thrb  
Affinity Capture-MS Mus musculus
11 MAPT  
Reconstituted Complex Homo sapiens
12 Ywhaz 22631
Affinity Capture-MS Mus musculus
13 Tfe3  
Affinity Capture-MS Mus musculus
14 Uchl5 56207
Co-fractionation Mus musculus
15 Atg16l1  
Affinity Capture-MS Mus musculus
16 Rps16 20055
Co-fractionation Mus musculus
17 Mettl21e  
Affinity Capture-MS Mus musculus
18 Fancd2  
Affinity Capture-MS Mus musculus
19 Ywhae 22627
Affinity Capture-MS Mus musculus
20 Traf3  
Proximity Label-MS Mus musculus
View the network image/svg+xml
 Pathways in which Eef1g is involved
PathwayEvidenceSource
Eukaryotic Translation Elongation IEA Reactome
Metabolism of proteins IEA Reactome
Translation IEA Reactome





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