Gene description for SSTR1
Gene name somatostatin receptor 1
Gene symbol SSTR1
Other names/aliases SRIF-2
SS-1-R
SS1-R
SS1R
Species Homo sapiens
 Database cross references - SSTR1
ExoCarta ExoCarta_6751
Vesiclepedia VP_6751
Entrez Gene 6751
HGNC 11330
MIM 182451
UniProt P30872  
 SSTR1 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for SSTR1
Molecular Function
    somatostatin receptor activity GO:0004994 IBA
    somatostatin receptor activity GO:0004994 IDA
    protein binding GO:0005515 IPI
    neuropeptide binding GO:0042923 IBA
Biological Process
    G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger GO:0007187 IEA
    glutamate receptor signaling pathway GO:0007215 IEA
    neuropeptide signaling pathway GO:0007218 IBA
    spermatogenesis GO:0007283 IEA
    negative regulation of cell population proliferation GO:0008285 IEA
    cerebellum development GO:0021549 IEA
    forebrain development GO:0030900 IEA
    somatostatin signaling pathway GO:0038170 IEA
    response to starvation GO:0042594 IEA
    cellular response to estradiol stimulus GO:0071392 IBA
    cellular response to leukemia inhibitory factor GO:1990830 IEA
Subcellular Localization
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 TAS
    neuron projection GO:0043005 IBA
 Experiment description of studies that identified SSTR1 in exosomes
1
Experiment ID 237
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for SSTR1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 LRRC8E 80131
Affinity Capture-MS Homo sapiens
2 TMEM259 91304
Affinity Capture-MS Homo sapiens
3 CYP51A1 1595
Affinity Capture-MS Homo sapiens
4 PRMT5 10419
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
5 SUPT16H 11198
Affinity Capture-MS Homo sapiens
6 RNF185  
Affinity Capture-MS Homo sapiens
7 SSRP1 6749
Affinity Capture-MS Homo sapiens
8 SLC27A3 11000
Affinity Capture-MS Homo sapiens
9 CORT  
Protein-peptide Homo sapiens
10 ARL8B 55207
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



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