Gene description for Rab13
Gene name RAB13, member RAS oncogene family
Gene symbol Rab13
Other names/aliases 0610007N03Rik
B230212B15Rik
Species Mus musculus
 Database cross references - Rab13
ExoCarta ExoCarta_68328
Entrez Gene 68328
UniProt Q9DD03  
 Rab13 identified in exosomes derived from the following tissue/cell type
Embryonic fibroblasts 18494037    
 Gene ontology annotations for Rab13
Molecular Function
    GTPase activity GO:0003924 TAS
    nucleotide binding GO:0000166 IEA
    GTP binding GO:0005525 ISO
    protein kinase A catalytic subunit binding GO:0034236 ISO
Biological Process
    intracellular protein transport GO:0006886 TAS
    protein transport GO:0015031 IEA
    establishment of Sertoli cell barrier GO:0097368 ISO
    transport GO:0006810 IEA
    bicellular tight junction assembly GO:0070830 ISO
    small GTPase mediated signal transduction GO:0007264 IEA
    endocytic recycling GO:0032456 ISO
    metabolic process GO:0008152 ISO
    endosomal transport GO:0016197 ISO
    cortical actin cytoskeleton organization GO:0030866 ISO
    protein kinase A signaling GO:0010737 ISO
    Rab protein signal transduction GO:0032482 IBA
    establishment of protein localization to plasma membrane GO:0090002 ISO
    protein localization to cell leading edge GO:1902463 IMP
    cellular response to insulin stimulus GO:0032869 ISO
    neuron projection development GO:0031175 ISO
    endothelial cell chemotaxis GO:0035767 IMP
    protein localization to plasma membrane GO:0072659 ISO
Subcellular Localization
    cell projection GO:0042995 IEA
    intracellular GO:0005622 IMP
    extrinsic component of plasma membrane GO:0019897 TAS
    cell junction GO:0030054 IEA
    trans-Golgi network GO:0005802 ISO
    endosome GO:0005768 IBA
    insulin-responsive compartment GO:0032593 ISO
    membrane GO:0016020 IEA
    Golgi apparatus GO:0005794 IDA
    plasma membrane GO:0005886 ISO
    cytoplasm GO:0005737 ISO
    neuron projection GO:0043005 ISO
    bicellular tight junction GO:0005923 ISO
    lateral plasma membrane GO:0016328 ISO
    endocytic vesicle GO:0030139 ISO
    cell-cell junction GO:0005911 IDA
    cytoplasmic membrane-bounded vesicle GO:0016023 TAS
    cytoplasmic vesicle GO:0031410 ISO
    recycling endosome GO:0055037 ISO
    extracellular exosome GO:0070062 ISO
    cell GO:0005623 IMP
    lamellipodium GO:0030027 IDA
 Experiment description of studies that identified Rab13 in exosomes
1
Experiment ID 73
ISEV standards
EM
EV Biophysical techniques
HSP70|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 18494037    
Organism Mus musculus
Experiment description Difference gel electrophoresis analysis of Ras-transformed fibroblast cell-derived exosomes.
Authors Ji H, Erfani N, Tauro BJ, Kapp EA, Zhu HJ, Moritz RL, Lim JW, Simpson RJ
Journal name ELEC
Publication year 2008
Sample Embryonic fibroblasts
Sample name NIH3T3
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LCQ DECA]
Western blotting
 Protein-protein interactions for Rab13
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SMURF2  
Affinity Capture-Luminescence Homo sapiens
2 SMAD4  
Affinity Capture-Luminescence Homo sapiens
3 TGFBR1  
Affinity Capture-Luminescence Homo sapiens
View the network image/svg+xml
 Pathways in which Rab13 is involved
PathwayEvidenceSource
Translocation of GLUT4 to the plasma membrane IEA Reactome





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