Gene description for Vps36
Gene name vacuolar protein sorting 36 (yeast)
Gene symbol Vps36
Other names/aliases 1700010A24Rik
2210415M20Rik
2810408E15Rik
Eap45
Species Mus musculus
 Database cross references - Vps36
ExoCarta ExoCarta_70160
Vesiclepedia VP_70160
Entrez Gene 70160
UniProt Q91XD6  
 Vps36 identified in exosomes derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Vps36
Molecular Function
    protein C-terminus binding GO:0008022 ISO
    phosphatidylinositol-3-phosphate binding GO:0032266 IEA
    lipid binding GO:0008289 IEA
    ubiquitin binding GO:0043130 ISO
Biological Process
    transport GO:0006810 IEA
    protein transport GO:0015031 IEA
    transcription, DNA-templated GO:0006351 IEA
    regulation of transcription, DNA-templated GO:0006355 IEA
    endosomal transport GO:0016197 IC
Subcellular Localization
    late endosome membrane GO:0031902 ISO
    extracellular exosome GO:0070062 ISO
    intracellular GO:0005622 IC
    cytoplasm GO:0005737 IEA
    cell GO:0005623 IC
    late endosome GO:0005770 IDA
    endosome GO:0005768 ISO
    nucleus GO:0005634 IEA
    cytosol GO:0005829 ISO
    membrane GO:0016020 IEA
    lysosome GO:0005764 IDA
 Experiment description of studies that identified Vps36 in exosomes
1
Experiment ID 907
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Vps36
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Vps36 is involved
PathwayEvidenceSource
Endosomal Sorting Complex Required For Transport (ESCRT) IEA Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here