Gene description for Pdia6
Gene name protein disulfide isomerase associated 6
Gene symbol Pdia6
Other names/aliases 1700015E05Rik
AL023058
C77895
CaBP5
P5
Txndc7
Species Mus musculus
 Database cross references - Pdia6
ExoCarta ExoCarta_71853
Entrez Gene 71853
UniProt Q922R8  
 Pdia6 identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Pdia6
Molecular Function
    isomerase activity GO:0016853 IEA
    protein disulfide isomerase activity GO:0003756 IBA
Biological Process
    protein folding GO:0006457 IBA
    response to endoplasmic reticulum stress GO:0034976 IBA
    cell redox homeostasis GO:0045454 IEA
Subcellular Localization
    membrane GO:0016020 IEA
    endoplasmic reticulum-Golgi intermediate compartment GO:0005793 ISO
    smooth endoplasmic reticulum GO:0005790 ISO
    extracellular exosome GO:0070062 ISO
    endoplasmic reticulum lumen GO:0005788 ISO
    endoplasmic reticulum GO:0005783 IEA
    endoplasmic reticulum chaperone complex GO:0034663 IDA
    plasma membrane GO:0005886 IEA
 Experiment description of studies that identified Pdia6 in exosomes
1
Experiment ID 188
ISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Pdia6
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Pdia6 is involved
No pathways found





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