Gene description for Erp44
Gene name endoplasmic reticulum protein 44
Gene symbol Erp44
Other names/aliases 1110001E24Rik
Species Mus musculus
 Database cross references - Erp44
ExoCarta ExoCarta_76299
Entrez Gene 76299
UniProt Q9D1Q6  
 Erp44 identified in exosomes derived from the following tissue/cell type
Neural stem cells 25242146    
 Gene ontology annotations for Erp44
Molecular Function
    protein binding GO:0005515 IPI
    protein disulfide isomerase activity GO:0003756 ISO
Biological Process
    response to unfolded protein GO:0006986 ISO
    cell redox homeostasis GO:0045454 IEA
    protein folding GO:0006457 ISO
    glycoprotein metabolic process GO:0009100 ISO
    response to endoplasmic reticulum stress GO:0034976 ISO
Subcellular Localization
    endoplasmic reticulum lumen GO:0005788 ISO
    endoplasmic reticulum GO:0005783 IEA
    extracellular exosome GO:0070062 ISO
    endoplasmic reticulum-Golgi intermediate compartment GO:0005793 ISO
    endoplasmic reticulum membrane GO:0005789 ISO
    cell surface GO:0009986 ISO
 Experiment description of studies that identified Erp44 in exosomes
Experiment ID 263
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25242146    
Organism Mus musculus
Experiment description Extracellular Vesicles from Neural Stem Cells Transfer IFN-γ via Ifngr1 to Activate Stat1 Signaling in Target Cells
Authors Chiara Cossetti, Nunzio Iraci, Tim R. Mercer, Tommaso Leonardi, Emanuele Alpi, Denise Drago, Clara Alfaro-Cervello, Harpreet K. Saini, Matthew P. Davis, Julia Schaeffer, Beatriz Vega, Matilde Stefanini, CongJian Zhao, Werner Muller, Jose Manuel Garcia-Verdugo, Suresh Mathivanan, Angela Bachi, Anton J. Enright, John S. Mattick, Stefano Pluchino
Journal name Molecular Cell
Publication year 2014
Sample Neural stem cells
Sample name NPCs - Th1 treated
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.13-1.20 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Erp44
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Erp44 is involved
No pathways found

Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here