Gene description for Tceb2
Gene name transcription elongation factor B (SIII), polypeptide 2
Gene symbol Tceb2
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Tceb2
ExoCarta ExoCarta_81807
Entrez Gene 81807
UniProt P62870  
 Tceb2 identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
Reticulocytes 21828046    
 Gene ontology annotations for Tceb2
Molecular Function
    transcription coactivator activity GO:0003713 IDA
    ubiquitin-protein transferase activity GO:0004842 IC
    protein complex binding GO:0032403 IPI
    ubiquitin protein ligase binding GO:0031625 ISO
Biological Process
    positive regulation of transcription from RNA polymerase II promoter GO:0045944 IDA
    transcription elongation from RNA polymerase II promoter GO:0006368 IBA
    protein ubiquitination GO:0016567 IEA
Subcellular Localization
    VCB complex GO:0030891 IDA
    elongin complex GO:0070449 ISO
    extracellular exosome GO:0070062 ISO
    Cul5-RING ubiquitin ligase complex GO:0031466 ISO
    Cul2-RING ubiquitin ligase complex GO:0031462 ISO
    transcription factor complex GO:0005667 IDA
 Experiment description of studies that identified Tceb2 in exosomes
1
Experiment ID 97
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
2
Experiment ID 98
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Tceb2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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