Gene description for IQCG
Gene name IQ motif containing G
Gene symbol IQCG
Other names/aliases CFAP122
DRC9
Species Homo sapiens
 Database cross references - IQCG
ExoCarta ExoCarta_84223
Vesiclepedia VP_84223
Entrez Gene 84223
HGNC 25251
MIM 612477
UniProt Q9H095  
 IQCG identified in exosomes derived from the following tissue/cell type
Urine 19056867    
Urine 21595033    
Urine 21595033    
Urine 21595033    
 Gene ontology annotations for IQCG
Molecular Function
    calmodulin binding GO:0005516 IDA
    Hsp70 protein binding GO:0030544 IPI
Biological Process
    spermatid development GO:0007286 ISS
    sperm axoneme assembly GO:0007288 IBA
    sperm axoneme assembly GO:0007288 ISS
    cilium organization GO:0044782 IBA
Subcellular Localization
    manchette GO:0002177 ISS
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    cytosol GO:0005829 IDA
    actin cytoskeleton GO:0015629 IDA
    motile cilium GO:0031514 ISS
    sperm flagellum GO:0036126 IBA
    sperm flagellum GO:0036126 ISS
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified IQCG in exosomes
1
Experiment ID 63
MISEV standards
Biophysical techniques
AQP2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
2
Experiment ID 193
MISEV standards
EM
Biophysical techniques
CD63|CD9
Enriched markers
PHB
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 194
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of basement membrane nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
4
Experiment ID 195
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of early IgA nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for IQCG
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CALM2 805
Two-hybrid Homo sapiens
2 BAG6 7917
Two-hybrid Homo sapiens
3 CALM3 808
Two-hybrid Homo sapiens
4 CALM1 801
Two-hybrid Homo sapiens
5 GSK3B 2932
Two-hybrid Homo sapiens
6 TP53 7157
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which IQCG is involved
No pathways found





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