Gene description for CD163
Gene name CD163 molecule
Gene symbol CD163
Other names/aliases M130
MM130
Species Homo sapiens
 Database cross references - CD163
ExoCarta ExoCarta_9332
Entrez Gene 9332
HGNC 1631
MIM 605545
UniProt Q86VB7  
 CD163 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for CD163
Molecular Function
    protein binding GO:0005515 IPI
    scavenger receptor activity GO:0005044 NAS
Biological Process
    acute-phase response GO:0006953 IEA
    receptor-mediated endocytosis GO:0006898 TAS
Subcellular Localization
    integral component of plasma membrane GO:0005887 TAS
    plasma membrane GO:0005886 TAS
    extracellular region GO:0005576 IEA
    endocytic vesicle membrane GO:0030666 TAS
 Experiment description of studies that identified CD163 in exosomes
1
Experiment ID 217
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
CD81|CD9|CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CD163
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CSNK2B 1460
Invivo Homo sapiens
Invitro Homo sapiens
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which CD163 is involved
PathwayEvidenceSource
Scavenging of heme from plasma TAS Reactome





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