Gene description for Nans
Gene name N-acetylneuraminic acid synthase (sialic acid synthase)
Gene symbol Nans
Other names/aliases 4632418E04Rik
BB056474
Sas
Species Mus musculus
 Database cross references - Nans
ExoCarta ExoCarta_94181
Entrez Gene 94181
 Nans identified in exosomes derived from the following tissue/cell type
Brain cancer cells 19109410    
 Gene ontology annotations for Nans
Molecular Function
    N-acylneuraminate-9-phosphate synthase activity GO:0047444 IDA
Subcellular Localization
    cytosol GO:0005829 IDA
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Nans in exosomes
1
Experiment ID 26
ISEV standards
EM
EV Biophysical techniques
Alix|GAPDH|HSP70
EV Cytosolic markers
CD9
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19109410    
Organism Mus musculus
Experiment description Proteomic and immunologic analyses of brain tumor exosomes.
Authors Graner MW, Alzate O, Dechkovskaia AM, Keene JD, Sampson JH, Mitchell DA, Bigner DD
Journal name FASEB
Publication year 2008
Sample Brain cancer cells
Sample name SMA560vIII
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.13-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
 Protein-protein interactions for Nans
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Nans is involved
No pathways found





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