Gene description for Mthfd1
Gene name	methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase
Gene symbol	Mthfd1
Other names/aliases	Dcs E430024A07Rik Mthfd
Species	Mus musculus
Database cross references - Mthfd1
ExoCarta	ExoCarta_108156
Entrez Gene	108156
UniProt	Q922D8
Mthfd1 identified in exosomes derived from the following tissue/cell type
Pancreatic cells	19351151

Gene ontology annotations for Mthfd1

Molecular Function     ligase activity GO:0016874 IEA     methylenetetrahydrofolate dehydrogenase (NADP+) activity GO:0004488 IBA     methylenetetrahydrofolate dehydrogenase (NAD+) activity GO:0004487 IDA     formate-tetrahydrofolate ligase activity GO:0004329 IMP     catalytic activity GO:0003824 IEA     hydrolase activity GO:0016787 IEA     ATP binding GO:0005524 IEA     methenyltetrahydrofolate cyclohydrolase activity GO:0004477 IBA     oxidoreductase activity GO:0016491 IEA     nucleotide binding GO:0000166 IEA Biological Process     heart development GO:0007507 IMP     purine nucleotide biosynthetic process GO:0006164 IMP     methionine biosynthetic process GO:0009086 ISO     metabolic process GO:0008152 IEA     tetrahydrofolate interconversion GO:0035999 IMP     methionine metabolic process GO:0006555 IMP     neural tube closure GO:0001843 IMP     histidine biosynthetic process GO:0000105 IEA     serine family amino acid biosynthetic process GO:0009070 ISO     somite development GO:0061053 IMP     oxidation-reduction process GO:0055114 IBA     one-carbon metabolic process GO:0006730 ISO     10-formyltetrahydrofolate biosynthetic process GO:0009257 IMP     folic acid-containing compound biosynthetic process GO:0009396 IEA     cellular amino acid biosynthetic process GO:0008652 IEA     neutrophil homeostasis GO:0001780 IMP     transsulfuration GO:0019346 IMP     serine family amino acid metabolic process GO:0009069 IMP Subcellular Localization     mitochondrion GO:0005739 IDA     cytosol GO:0005829 IBA     cytoplasm GO:0005737 IEA     extracellular exosome GO:0070062 ISO     membrane GO:0016020 ISO