Gene description for Src
Gene name Rous sarcoma oncogene
Gene symbol Src
Other names/aliases AW259666
pp60c-src
Species Mus musculus
 Database cross references - Src
ExoCarta ExoCarta_20779
Vesiclepedia VP_20779
Entrez Gene 20779
UniProt P05480  
 Src identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Src
Molecular Function
    protein kinase activity GO:0004672 IDA
    protein kinase activity GO:0004672 IMP
    protein kinase activity GO:0004672 ISO
    protein tyrosine kinase activity GO:0004713 EXP
    protein tyrosine kinase activity GO:0004713 IDA
    protein tyrosine kinase activity GO:0004713 IMP
    protein tyrosine kinase activity GO:0004713 ISO
    protein tyrosine kinase activity GO:0004713 TAS
    non-membrane spanning protein tyrosine kinase activity GO:0004715 IBA
    non-membrane spanning protein tyrosine kinase activity GO:0004715 IEA
    non-membrane spanning protein tyrosine kinase activity GO:0004715 ISO
    protein kinase C binding GO:0005080 IEA
    protein kinase C binding GO:0005080 ISO
    signaling receptor binding GO:0005102 IBA
    signaling receptor binding GO:0005102 ISO
    insulin receptor binding GO:0005158 IEA
    insulin receptor binding GO:0005158 ISO
    integrin binding GO:0005178 IEA
    integrin binding GO:0005178 ISO
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IEA
    phospholipase activator activity GO:0016004 IEA
    phospholipase activator activity GO:0016004 ISO
    kinase activity GO:0016301 IMP
    enzyme binding GO:0019899 ISO
    protein kinase binding GO:0019901 ISO
    protein domain specific binding GO:0019904 IPI
    heme binding GO:0020037 ISO
    heme binding GO:0020037 ISS
    nuclear estrogen receptor binding GO:0030331 IEA
    nuclear estrogen receptor binding GO:0030331 ISO
    histone H3Y41 kinase activity GO:0035401 IEA
    SH2 domain binding GO:0042169 IEA
    SH2 domain binding GO:0042169 ISO
    phospholipase binding GO:0043274 IEA
    phospholipase binding GO:0043274 ISO
    transmembrane transporter binding GO:0044325 IEA
    transmembrane transporter binding GO:0044325 ISO
    protein-containing complex binding GO:0044877 ISO
    ephrin receptor binding GO:0046875 IPI
    ephrin receptor binding GO:0046875 ISO
    cell adhesion molecule binding GO:0050839 ISO
    phosphoprotein binding GO:0051219 IEA
    phosphoprotein binding GO:0051219 ISO
    BMP receptor binding GO:0070700 IEA
    BMP receptor binding GO:0070700 ISO
    connexin binding GO:0071253 IPI
    scaffold protein binding GO:0097110 IPI
    scaffold protein binding GO:0097110 ISO
    histone H2AXY142 kinase activity GO:0140801 IEA
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 IEA
    primary ovarian follicle growth GO:0001545 IEA
    primary ovarian follicle growth GO:0001545 ISO
    positive regulation of cytokine production GO:0001819 IEA
    positive regulation of cytokine production GO:0001819 ISO
    immune system process GO:0002376 IEA
    chromatin remodeling GO:0006338 IEA
    protein phosphorylation GO:0006468 IDA
    cell adhesion GO:0007155 IBA
    epidermal growth factor receptor signaling pathway GO:0007173 IBA
    epidermal growth factor receptor signaling pathway GO:0007173 IEA
    transforming growth factor beta receptor signaling pathway GO:0007179 IEA
    transforming growth factor beta receptor signaling pathway GO:0007179 ISO
    integrin-mediated signaling pathway GO:0007229 IEA
    integrin-mediated signaling pathway GO:0007229 ISO
    spermatogenesis GO:0007283 IEA
    learning or memory GO:0007611 IEA
    positive regulation of cell population proliferation GO:0008284 ISO
    response to xenobiotic stimulus GO:0009410 IEA
    response to mechanical stimulus GO:0009612 IEA
    response to acidic pH GO:0010447 IEA
    positive regulation of gene expression GO:0010628 ISO
    negative regulation of gene expression GO:0010629 IEA
    negative regulation of gene expression GO:0010629 ISO
    regulation of epithelial cell migration GO:0010632 ISO
    positive regulation of epithelial cell migration GO:0010634 IEA
    positive regulation of epithelial cell migration GO:0010634 ISO
    positive regulation of glucose metabolic process GO:0010907 IEA
    positive regulation of glucose metabolic process GO:0010907 ISO
    positive regulation of protein processing GO:0010954 IGI
    skeletal muscle cell proliferation GO:0014856 IEA
    positive regulation of smooth muscle cell migration GO:0014911 IEA
    positive regulation of smooth muscle cell migration GO:0014911 ISO
    phosphorylation GO:0016310 IMP
    cell migration GO:0016477 IMP
    peptidyl-tyrosine phosphorylation GO:0018108 IDA
    peptidyl-tyrosine phosphorylation GO:0018108 IMP
    peptidyl-tyrosine phosphorylation GO:0018108 ISO
    peptidyl-tyrosine phosphorylation GO:0018108 ISO
    regulation of cell-cell adhesion GO:0022407 IEA
    regulation of cell-cell adhesion GO:0022407 ISO
    cell differentiation GO:0030154 IBA
    forebrain development GO:0030900 IGI
    negative regulation of protein-containing complex assembly GO:0031333 IEA
    negative regulation of protein-containing complex assembly GO:0031333 ISO
    protein destabilization GO:0031648 IMP
    response to nutrient levels GO:0031667 IEA
    negative regulation of telomere maintenance GO:0032205 IEA
    negative regulation of telomere maintenance via telomerase GO:0032211 ISO
    cellular response to insulin stimulus GO:0032869 IEA
    regulation of intracellular estrogen receptor signaling pathway GO:0033146 IMP
    regulation of toll-like receptor 3 signaling pathway GO:0034139 IEA
    regulation of toll-like receptor 3 signaling pathway GO:0034139 ISO
    adherens junction organization GO:0034332 IEA
    substrate adhesion-dependent cell spreading GO:0034446 IDA
    cellular response to reactive oxygen species GO:0034614 IDA
    positive regulation of dephosphorylation GO:0035306 IEA
    positive regulation of dephosphorylation GO:0035306 ISO
    negative regulation of hippo signaling GO:0035331 IEA
    negative regulation of hippo signaling GO:0035331 ISO
    intracellular signal transduction GO:0035556 IGI
    intracellular signal transduction GO:0035556 ISO
    osteoclast development GO:0036035 IGI
    cellular response to platelet-derived growth factor stimulus GO:0036120 IDA
    angiotensin-activated signaling pathway GO:0038166 IGI
    odontogenesis GO:0042476 IMP
    positive regulation of apoptotic process GO:0043065 IEA
    positive regulation of apoptotic process GO:0043065 ISO
    negative regulation of apoptotic process GO:0043066 ISO
    stress fiber assembly GO:0043149 IEA
    stress fiber assembly GO:0043149 ISO
    regulation of protein binding GO:0043393 IDA
    transcytosis GO:0045056 IEA
    transcytosis GO:0045056 ISO
    bone resorption GO:0045453 IMP
    bone resorption GO:0045453 IMP
    positive regulation of Notch signaling pathway GO:0045747 IDA
    positive regulation of Notch signaling pathway GO:0045747 ISO
    positive regulation of bone resorption GO:0045780 IEA
    positive regulation of bone resorption GO:0045780 ISO
    positive regulation of cell adhesion GO:0045785 IEA
    positive regulation of cell adhesion GO:0045785 ISO
    positive regulation of glycolytic process GO:0045821 IDA
    positive regulation of Ras protein signal transduction GO:0046579 IEA
    positive regulation of Ras protein signal transduction GO:0046579 ISO
    positive regulation of insulin receptor signaling pathway GO:0046628 IEA
    positive regulation of insulin receptor signaling pathway GO:0046628 ISO
    protein autophosphorylation GO:0046777 ISO
    platelet-derived growth factor receptor signaling pathway GO:0048008 IEA
    neurotrophin TRK receptor signaling pathway GO:0048011 IEA
    neurotrophin TRK receptor signaling pathway GO:0048011 ISO
    focal adhesion assembly GO:0048041 IEA
    focal adhesion assembly GO:0048041 ISO
    oogenesis GO:0048477 IMP
    positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 IGI
    positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 ISO
    progesterone receptor signaling pathway GO:0050847 IBA
    progesterone receptor signaling pathway GO:0050847 IEA
    progesterone receptor signaling pathway GO:0050847 ISO
    positive regulation of small GTPase mediated signal transduction GO:0051057 ISO
    positive regulation of protein transport GO:0051222 IEA
    positive regulation of protein transport GO:0051222 ISO
    response to mineralocorticoid GO:0051385 IEA
    myoblast proliferation GO:0051450 IEA
    response to electrical stimulus GO:0051602 IEA
    negative regulation of focal adhesion assembly GO:0051895 IEA
    negative regulation of focal adhesion assembly GO:0051895 ISO
    positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction GO:0051897 IEA
    positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction GO:0051897 ISO
    negative regulation of mitochondrial depolarization GO:0051902 IEA
    negative regulation of mitochondrial depolarization GO:0051902 ISO
    uterus development GO:0060065 IMP
    branching involved in mammary gland duct morphogenesis GO:0060444 IMP
    regulation of cell projection assembly GO:0060491 IGI
    intestinal epithelial cell development GO:0060576 IDA
    intestinal epithelial cell development GO:0060576 ISO
    interleukin-6-mediated signaling pathway GO:0070102 IDA
    interleukin-6-mediated signaling pathway GO:0070102 ISO
    cellular response to hydrogen peroxide GO:0070301 IMP
    positive regulation of ERK1 and ERK2 cascade GO:0070374 IMP
    positive regulation of ERK1 and ERK2 cascade GO:0070374 ISO
    response to interleukin-1 GO:0070555 IEA
    response to interleukin-1 GO:0070555 ISO
    cellular response to lipopolysaccharide GO:0071222 IEA
    cellular response to peptide hormone stimulus GO:0071375 IGI
    cellular response to progesterone stimulus GO:0071393 IEA
    cellular response to progesterone stimulus GO:0071393 ISO
    cellular response to fatty acid GO:0071398 IEA
    cellular response to hypoxia GO:0071456 IEA
    cellular response to fluid shear stress GO:0071498 IMP
    cellular response to transforming growth factor beta stimulus GO:0071560 IGI
    positive regulation of podosome assembly GO:0071803 IDA
    positive regulation of podosome assembly GO:0071803 IGI
    DNA biosynthetic process GO:0071897 IEA
    DNA biosynthetic process GO:0071897 ISO
    positive regulation of protein serine/threonine kinase activity GO:0071902 ISO
    regulation of heart rate by cardiac conduction GO:0086091 IGI
    positive regulation of canonical Wnt signaling pathway GO:0090263 IGI
    cell-cell adhesion GO:0098609 IEA
    positive regulation of protein localization to nucleus GO:1900182 IGI
    positive regulation of intracellular signal transduction GO:1902533 ISO
    positive regulation of TORC1 signaling GO:1904263 IEA
    positive regulation of TORC1 signaling GO:1904263 ISO
    positive regulation of vascular associated smooth muscle cell proliferation GO:1904707 IEA
    positive regulation of vascular associated smooth muscle cell proliferation GO:1904707 ISO
    cellular response to prolactin GO:1990646 IEA
    negative regulation of cysteine-type endopeptidase activity GO:2000117 ISO
    positive regulation of male germ cell proliferation GO:2000256 IEA
    positive regulation of male germ cell proliferation GO:2000256 ISO
    positive regulation of ovarian follicle development GO:2000386 IEA
    positive regulation of ovarian follicle development GO:2000386 ISO
    positive regulation of lamellipodium morphogenesis GO:2000394 IEA
    positive regulation of lamellipodium morphogenesis GO:2000394 ISO
    positive regulation of platelet-derived growth factor receptor-beta signaling pathway GO:2000588 IMP
    regulation of early endosome to late endosome transport GO:2000641 IEA
    regulation of early endosome to late endosome transport GO:2000641 ISO
    negative regulation of anoikis GO:2000811 IEA
    negative regulation of anoikis GO:2000811 ISO
    negative regulation of extrinsic apoptotic signaling pathway GO:2001237 IBA
    negative regulation of extrinsic apoptotic signaling pathway GO:2001237 IEA
    negative regulation of extrinsic apoptotic signaling pathway GO:2001237 ISO
    negative regulation of intrinsic apoptotic signaling pathway GO:2001243 IBA
    negative regulation of intrinsic apoptotic signaling pathway GO:2001243 IEA
    negative regulation of intrinsic apoptotic signaling pathway GO:2001243 ISO
    regulation of caveolin-mediated endocytosis GO:2001286 IEA
    regulation of caveolin-mediated endocytosis GO:2001286 ISO
Subcellular Localization
    podosome GO:0002102 IDA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 ISO
    nucleoplasm GO:0005654 TAS
    cytoplasm GO:0005737 IDA
    cytoplasm GO:0005737 ISO
    mitochondrion GO:0005739 IDA
    mitochondrion GO:0005739 ISO
    mitochondrial inner membrane GO:0005743 IDA
    mitochondrial inner membrane GO:0005743 ISO
    lysosome GO:0005764 IEA
    lysosome GO:0005764 ISO
    late endosome GO:0005770 IEA
    late endosome GO:0005770 ISO
    cytosol GO:0005829 ISO
    cytosol GO:0005829 TAS
    cytoskeleton GO:0005856 IDA
    actin filament GO:0005884 IDA
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IDA
    plasma membrane GO:0005886 ISO
    plasma membrane GO:0005886 TAS
    caveola GO:0005901 IDA
    caveola GO:0005901 ISO
    cell-cell junction GO:0005911 ISS
    focal adhesion GO:0005925 IMP
    membrane GO:0016020 IMP
    cell junction GO:0030054 ISO
    cell junction GO:0030054 ISS
    ruffle membrane GO:0032587 IDA
    neuronal cell body GO:0043025 IEA
    neuronal cell body GO:0043025 ISO
    dendritic growth cone GO:0044294 IEA
    dendritic growth cone GO:0044294 ISO
    perinuclear region of cytoplasm GO:0048471 IDA
    perinuclear region of cytoplasm GO:0048471 ISO
    synaptic membrane GO:0097060 IEA
    synaptic membrane GO:0097060 ISO
    glutamatergic synapse GO:0098978 IEA
    glutamatergic synapse GO:0098978 ISO
    postsynaptic specialization, intracellular component GO:0099091 IEA
    postsynaptic specialization, intracellular component GO:0099091 ISO
    dendritic filopodium GO:1902737 IEA
    dendritic filopodium GO:1902737 ISO
 Experiment description of studies that identified Src in sEVs
1
Experiment ID 907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Src
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Ptpn2  
Co-fractionation Mus musculus
2 Akt1  
Affinity Capture-Western Mus musculus
Affinity Capture-Western Mus musculus
3 Nmt1  
Co-fractionation Mus musculus
4 Atxn2 20239
Affinity Capture-Western Mus musculus
5 Hcn2  
Co-fractionation Mus musculus
6 Ep300  
Affinity Capture-Western Mus musculus
Affinity Capture-Western Mus musculus
7 Insr  
Affinity Capture-Western Mus musculus
8 Eno1 13806
Biochemical Activity Mus musculus
Biochemical Activity Mus musculus
9 Ptk2b  
Affinity Capture-Western Mus musculus
Affinity Capture-Western Mus musculus
10 Arrb1  
Affinity Capture-Western Mus musculus
11 Srcin1  
Co-fractionation Mus musculus
12 Map1lc3b  
Affinity Capture-Western Mus musculus
13 Dvl2  
Affinity Capture-Western Mus musculus
Affinity Capture-Western Mus musculus
Biochemical Activity Mus musculus
14 Shank3  
Affinity Capture-MS Mus musculus
15 Tns3  
Co-fractionation Mus musculus
16 Tpt1 22070
Co-fractionation Mus musculus
17 Itga2  
Affinity Capture-Western Mus musculus
18 Nfatc1  
Affinity Capture-Western Mus musculus
19 Ptk2  
Affinity Capture-Western Mus musculus
Affinity Capture-Western Mus musculus
Co-fractionation Mus musculus
20 Jak2 16452
Affinity Capture-Western Mus musculus
21 Diap1 13367
Affinity Capture-Western Mus musculus
22 Csn2  
Biochemical Activity Mus musculus
23 Arrb2  
Affinity Capture-Western Mus musculus
Affinity Capture-Western Mus musculus
24 Grin2b  
Affinity Capture-Western Mus musculus
25 Kdr  
Affinity Capture-Western Mus musculus
Affinity Capture-Western Mus musculus
Affinity Capture-Western Mus musculus
26 Src 20779
Biochemical Activity Mus musculus
Biochemical Activity Mus musculus
27 Cav3  
Co-fractionation Mus musculus
Affinity Capture-Western Mus musculus
28 Agap2  
Affinity Capture-MS Mus musculus
29 Khdrbs1 20218
Biochemical Activity Mus musculus
Biochemical Activity Mus musculus
30 Inpp5d 16331
Affinity Capture-Western Mus musculus
31 S1pr1  
Affinity Capture-Western Mus musculus
32 Grin1  
Affinity Capture-Western Mus musculus
33 Prkce  
Affinity Capture-Western Mus musculus
Reconstituted Complex Mus musculus
34 Pik3c2a  
Biochemical Activity Mus musculus
35 Prkaca  
Biochemical Activity Mus musculus
36 Snx17  
Co-fractionation Mus musculus
37 Sh3bp2  
Biochemical Activity Mus musculus
38 Sstr3  
Proximity Label-MS Mus musculus
39 Egfr 13649
Affinity Capture-Western Mus musculus
40 Gfap  
Co-fractionation Mus musculus
41 Bcar1  
Affinity Capture-Western Mus musculus
42 Dab1  
Affinity Capture-MS Mus musculus
43 Efs  
Reconstituted Complex Mus musculus
44 Shroom2  
Co-fractionation Mus musculus
45 Cbl 12402
Affinity Capture-Western Mus musculus
Affinity Capture-Western Mus musculus
Affinity Capture-Western Mus musculus
Biochemical Activity Mus musculus
Affinity Capture-Western Mus musculus
Biochemical Activity Mus musculus
Affinity Capture-Western Mus musculus
46 Ptpn11 19247
Co-fractionation Mus musculus
47 Tub  
Co-fractionation Mus musculus
48 Skp2  
Affinity Capture-Western Mus musculus
View the network image/svg+xml
 Pathways in which Src is involved
PathwayEvidenceSource
Activated NTRK3 signals through PI3K IEA Reactome
Adaptive Immune System IEA Reactome
ADP signalling through P2Y purinoceptor 1 IEA Reactome
Autophagy IEA Reactome
Axon guidance IEA Reactome
C-type lectin receptors (CLRs) IEA Reactome
CD28 co-stimulation IEA Reactome
Cell Cycle IEA Reactome
Cell Cycle, Mitotic IEA Reactome
Cell surface interactions at the vascular wall IEA Reactome
CLEC7A (Dectin-1) signaling IEA Reactome
Costimulation by the CD28 family IEA Reactome
CTLA4 inhibitory signaling IEA Reactome
Cyclin D associated events in G1 IEA Reactome
DCC mediated attractive signaling IEA Reactome
Developmental Biology IEA Reactome
Downregulation of ERBB4 signaling IEA Reactome
Downstream signal transduction IEA Reactome
EPH-ephrin mediated repulsion of cells IEA Reactome
EPH-Ephrin signaling IEA Reactome
EPHA-mediated growth cone collapse IEA Reactome
EPHB-mediated forward signaling IEA Reactome
Ephrin signaling IEA Reactome
ESR-mediated signaling IEA Reactome
Extra-nuclear estrogen signaling IEA Reactome
Fcgamma receptor (FCGR) dependent phagocytosis IEA Reactome
FCGR activation IEA Reactome
G alpha (i) signalling events IEA Reactome
G1 Phase IEA Reactome
GAB1 signalosome IEA Reactome
Gap junction trafficking and regulation IEA Reactome
Gene expression (Transcription) IEA Reactome
Generic Transcription Pathway IEA Reactome
GP1b-IX-V activation signalling IEA Reactome
GPCR downstream signalling IEA Reactome
GRB2:SOS provides linkage to MAPK signaling for Integrins IEA Reactome
Hemostasis IEA Reactome
Immune System IEA Reactome
Innate Immune System IEA Reactome
Integrin signaling IEA Reactome
Intracellular signaling by second messengers IEA Reactome
L1CAM interactions IEA Reactome
Macroautophagy IEA Reactome
MAP2K and MAPK activation IEA Reactome
MAPK family signaling cascades IEA Reactome
MAPK1/MAPK3 signaling IEA Reactome
Membrane Trafficking IEA Reactome
MET activates PTK2 signaling IEA Reactome
MET promotes cell motility IEA Reactome
Mitophagy IEA Reactome
Mitotic G1 phase and G1/S transition IEA Reactome
Negative regulation of FGFR1 signaling IEA Reactome
Negative regulation of FGFR2 signaling IEA Reactome
Negative regulation of FGFR3 signaling IEA Reactome
Negative regulation of FGFR4 signaling IEA Reactome
Negative regulation of the PI3K/AKT network IEA Reactome
Nervous system development IEA Reactome
Netrin-1 signaling IEA Reactome
Nuclear signaling by ERBB4 IEA Reactome
p130Cas linkage to MAPK signaling for integrins IEA Reactome
PECAM1 interactions IEA Reactome
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling IEA Reactome
PIP3 activates AKT signaling IEA Reactome
Platelet activation, signaling and aggregation IEA Reactome
Platelet Aggregation (Plug Formation) IEA Reactome
RAF activation IEA Reactome
RAF/MAP kinase cascade IEA Reactome
Receptor Mediated Mitophagy IEA Reactome
Recycling pathway of L1 IEA Reactome
Regulation of gap junction activity IEA Reactome
Regulation of KIT signaling IEA Reactome
Regulation of RUNX3 expression and activity IEA Reactome
RET signaling IEA Reactome
RHO GTPase Effectors IEA Reactome
RHO GTPases Activate Formins IEA Reactome
RNA Polymerase II Transcription IEA Reactome
Selective autophagy IEA Reactome
Signal amplification IEA Reactome
Signal Transduction IEA Reactome
Signaling by EGFR IEA Reactome
Signaling by ERBB2 IEA Reactome
Signaling by ERBB4 IEA Reactome
Signaling by FGFR IEA Reactome
Signaling by FGFR1 IEA Reactome
Signaling by FGFR2 IEA Reactome
Signaling by FGFR3 IEA Reactome
Signaling by FGFR4 IEA Reactome
Signaling by GPCR IEA Reactome
Signaling by MET IEA Reactome
Signaling by NTRK3 (TRKC) IEA Reactome
Signaling by NTRKs IEA Reactome
Signaling by Nuclear Receptors IEA Reactome
Signaling by PDGF IEA Reactome
Signaling by Receptor Tyrosine Kinases IEA Reactome
Signaling by Rho GTPases IEA Reactome
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 IEA Reactome
Signaling by SCF-KIT IEA Reactome
Signaling by VEGF IEA Reactome
Spry regulation of FGF signaling IEA Reactome
Thrombin signalling through proteinase activated receptors (PARs) IEA Reactome
Transcriptional regulation by RUNX3 IEA Reactome
VEGFA-VEGFR2 Pathway IEA Reactome
VEGFR2 mediated cell proliferation IEA Reactome
Vesicle-mediated transport IEA Reactome





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