Gene description for MED4
Gene name mediator complex subunit 4
Gene symbol MED4
Other names/aliases ARC36
DRIP36
HSPC126
TRAP36
VDRIP
Species Homo sapiens
 Database cross references - MED4
ExoCarta ExoCarta_29079
Vesiclepedia VP_29079
Entrez Gene 29079
HGNC 17903
MIM 605718
UniProt Q9NPJ6  
 MED4 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
 Gene ontology annotations for MED4
Molecular Function
    transcription coregulator activity GO:0003712 IBA
    transcription coregulator activity GO:0003712 IDA
    transcription coactivator activity GO:0003713 IDA
    protein binding GO:0005515 IPI
    nuclear receptor coactivator activity GO:0030374 NAS
    nuclear vitamin D receptor binding GO:0042809 NAS
    nuclear thyroid hormone receptor binding GO:0046966 IDA
Biological Process
    regulation of transcription by RNA polymerase II GO:0006357 IBA
    transcription by RNA polymerase II GO:0006366 IDA
    positive regulation of transcription elongation by RNA polymerase II GO:0032968 NAS
    positive regulation of DNA-templated transcription GO:0045893 IDA
    RNA polymerase II preinitiation complex assembly GO:0051123 NAS
    positive regulation of transcription initiation by RNA polymerase II GO:0060261 IDA
    positive regulation of transcription initiation by RNA polymerase II GO:0060261 NAS
Subcellular Localization
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    membrane GO:0016020 HDA
    mediator complex GO:0016592 IDA
    core mediator complex GO:0070847 IBA
    core mediator complex GO:0070847 IPI
 Experiment description of studies that identified MED4 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for MED4
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
2 POLR2G 5436
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 MCRS1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
4 RIT1 6016
Negative Genetic Homo sapiens
5 CD3EAP  
Affinity Capture-MS Homo sapiens
6 MED17  
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 MED20 9477
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 PTPN22  
Proximity Label-MS Homo sapiens
9 KIFC3 3801
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
10 AES 166
Two-hybrid Homo sapiens
11 MED6  
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 RPA2 6118
Affinity Capture-MS Homo sapiens
13 MED29  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 QKI 9444
Affinity Capture-MS Homo sapiens
15 FBXL19  
Affinity Capture-MS Homo sapiens
16 MED9  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 MED13L 23389
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 SMARCE1 6605
Two-hybrid Homo sapiens
19 RECQL5  
Affinity Capture-MS Homo sapiens
20 PUM2 23369
Two-hybrid Homo sapiens
21 SCAF4 57466
Affinity Capture-MS Homo sapiens
22 MED24 9862
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 WDTC1 23038
Two-hybrid Homo sapiens
24 Med22  
Affinity Capture-MS Mus musculus
25 FTCD 10841
Two-hybrid Homo sapiens
26 MED12L  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 MED13 9969
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 NDE1 54820
Two-hybrid Homo sapiens
29 PPFIA3 8541
Affinity Capture-MS Homo sapiens
30 POLR2I 5438
Affinity Capture-MS Homo sapiens
31 CCDC14  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 AR 367
Proximity Label-MS Homo sapiens
33 FBXW7  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 CCDC138  
Affinity Capture-MS Homo sapiens
35 KRT40  
Affinity Capture-MS Homo sapiens
36 HGS 9146
Two-hybrid Homo sapiens
37 OIP5  
Two-hybrid Homo sapiens
38 CRCP  
Affinity Capture-MS Homo sapiens
39 MED22  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 GTF2B 2959
Affinity Capture-MS Homo sapiens
41 BRD4 23476
Affinity Capture-MS Homo sapiens
42 ATG16L1 55054
Affinity Capture-MS Homo sapiens
43 POLR2C 5432
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 MED27  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 POLR2M  
Affinity Capture-MS Homo sapiens
46 VDR  
Affinity Capture-MS Homo sapiens
47 SDCBP 6386
Two-hybrid Homo sapiens
48 POLR2H 5437
Affinity Capture-MS Homo sapiens
49 TAX1BP1 8887
Affinity Capture-MS Homo sapiens
50 IFT20 90410
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
51 C1orf216  
Two-hybrid Homo sapiens
52 POLR2K  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 MED1 5469
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
54 XRCC4  
Affinity Capture-MS Homo sapiens
55 MIB1 57534
Proximity Label-MS Homo sapiens
56 Asap1  
Two-hybrid Mus musculus
57 MED7  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
58 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
59 UXT 8409
Affinity Capture-MS Homo sapiens
60 EMD 2010
Affinity Capture-MS Homo sapiens
61 CTDP1 9150
Reconstituted Complex Homo sapiens
62 TNFAIP8 25816
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
63 C12orf49  
Positive Genetic Homo sapiens
64 GIT1 28964
Affinity Capture-MS Homo sapiens
65 LRRFIP1 9208
Two-hybrid Homo sapiens
66 TPTE2  
Proximity Label-MS Homo sapiens
67 APOA2 336
Affinity Capture-MS Homo sapiens
68 CENPE 1062
Affinity Capture-MS Homo sapiens
69 MED26  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
70 CCDC101  
Two-hybrid Homo sapiens
71 ARHGEF6 9459
Affinity Capture-MS Homo sapiens
72 MED25  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
73 Nup214  
Affinity Capture-MS Mus musculus
74 HECTD1 25831
Affinity Capture-MS Homo sapiens
75 GCC1 79571
Two-hybrid Homo sapiens
76 MED31  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
77 FOXJ3  
Two-hybrid Homo sapiens
78 PPM1G 5496
Co-fractionation Homo sapiens
79 TXLNB  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
80 NR1I3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
81 MED15  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
82 SNAP29 9342
Affinity Capture-MS Homo sapiens
83 POLR2B 5431
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
84 HNRNPD 3184
Affinity Capture-MS Homo sapiens
85 CHPF 79586
Affinity Capture-MS Homo sapiens
86 MAB21L3  
Two-hybrid Homo sapiens
87 TNFAIP8L1  
Two-hybrid Homo sapiens
88 COPS2 9318
Affinity Capture-MS Homo sapiens
89 CCNC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
90 TP53BP1 7158
Negative Genetic Homo sapiens
91 SMARCD1 6602
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
92 SEC13 6396
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
93 EPAS1  
Affinity Capture-MS Homo sapiens
94 FGF12  
Affinity Capture-MS Homo sapiens
95 POLR2E 5434
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
96 ACAD11 84129
Affinity Capture-MS Homo sapiens
97 SSX3  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
98 RPRD2  
Affinity Capture-MS Homo sapiens
99 CDK19 23097
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
100 RPRD1A  
Affinity Capture-MS Homo sapiens
101 SYCE2  
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
102 POLR2D  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
103 OBFC1 79991
Affinity Capture-MS Homo sapiens
104 HOMER1  
Affinity Capture-MS Homo sapiens
105 POLR2A 5430
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
106 POLR3E 55718
Affinity Capture-MS Homo sapiens
107 NXF1 10482
Affinity Capture-RNA Homo sapiens
108 AP2M1 1173
Two-hybrid Homo sapiens
109 HNF4A  
Proximity Label-MS Homo sapiens
110 MED10  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
111 TADA2A  
Affinity Capture-MS Homo sapiens
112 POLR1E  
Affinity Capture-MS Homo sapiens
113 RPA3 6119
Affinity Capture-MS Homo sapiens
114 NIN 51199
Proximity Label-MS Homo sapiens
115 RGPD5  
Affinity Capture-MS Homo sapiens
116 POLR2F  
Affinity Capture-MS Homo sapiens
117 IP6K3  
Two-hybrid Homo sapiens
118 NDC80 10403
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
119 PSMC5 5705
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
120 MED23 9439
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
121 AMOT 154796
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
122 DNAJB13  
Proximity Label-MS Homo sapiens
123 USHBP1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
124 PCM1 5108
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
125 CEBPA  
Protein-peptide Homo sapiens
126 ATF7IP2 80063
Two-hybrid Homo sapiens
127 BRD3 8019
Affinity Capture-MS Homo sapiens
128 MED14  
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
129 FRMD6 122786
Two-hybrid Homo sapiens
130 HUWE1 10075
Co-fractionation Homo sapiens
131 BIRC5  
Affinity Capture-MS Homo sapiens
132 MYH11 4629
Affinity Capture-MS Homo sapiens
133 MED11  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
134 TXLNA 200081
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
135 ARHGEF7 8874
Affinity Capture-MS Homo sapiens
136 DZIP3  
Affinity Capture-MS Homo sapiens
137 CTNNBL1 56259
Two-hybrid Homo sapiens
138 MED19  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
139 KIF21B 23046
Affinity Capture-MS Homo sapiens
140 ESR2  
Affinity Capture-MS Homo sapiens
141 PCBD2 84105
Two-hybrid Homo sapiens
142 HAUS1  
Two-hybrid Homo sapiens
143 POLR2J  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
144 RNF40 9810
Affinity Capture-MS Homo sapiens
145 CDK8 1024
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
146 CCHCR1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
147 POLR2L 5441
Affinity Capture-MS Homo sapiens
148 CCDC146  
Two-hybrid Homo sapiens
149 LRRCC1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
150 RPA1 6117
Affinity Capture-MS Homo sapiens
151 RPS21 6227
Cross-Linking-MS (XL-MS) Homo sapiens
152 Cep135  
Affinity Capture-MS Mus musculus
153 MED8  
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
154 RPAP2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
155 FAM184A 79632
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
156 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
157 C15orf59  
Affinity Capture-MS Homo sapiens
158 TRIP11 9321
Affinity Capture-MS Homo sapiens
159 NIFK 84365
Co-fractionation Homo sapiens
160 MED30  
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
161 MED16 10025
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
162 WWP2 11060
Biochemical Activity Homo sapiens
163 MED18  
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
164 MED21  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
165 TCL1B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
166 MED12  
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
167 TRIP4 9325
Affinity Capture-MS Homo sapiens
168 POLR3D  
Affinity Capture-MS Homo sapiens
169 ZCCHC10  
Affinity Capture-MS Homo sapiens
170 POLR3B 55703
Affinity Capture-MS Homo sapiens
171 PIH1D1  
Affinity Capture-MS Homo sapiens
172 ZNRD1  
Affinity Capture-MS Homo sapiens
173 KRAS 3845
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
174 POLR1D 51082
Affinity Capture-MS Homo sapiens
175 ZC3H13 23091
Affinity Capture-MS Homo sapiens
176 POLR3H  
Affinity Capture-MS Homo sapiens
177 PDRG1  
Affinity Capture-MS Homo sapiens
178 FAM13C  
Two-hybrid Homo sapiens
179 TADA2B  
Affinity Capture-MS Homo sapiens
180 MED28  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which MED4 is involved
PathwayEvidenceSource
Adipogenesis TAS Reactome
Adipogenesis IEA Reactome
Developmental Biology TAS Reactome
Developmental Biology IEA Reactome
Disease TAS Reactome
Epigenetic regulation by WDR5-containing histone modifying complexes TAS Reactome
Epigenetic regulation by WDR5-containing histone modifying complexes IEA Reactome
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes TAS Reactome
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes IEA Reactome
Epigenetic regulation of gene expression TAS Reactome
Epigenetic regulation of gene expression IEA Reactome
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes TAS Reactome
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes IEA Reactome
Gene expression (Transcription) TAS Reactome
Gene expression (Transcription) IEA Reactome
Generic Transcription Pathway TAS Reactome
Infectious disease TAS Reactome
Metabolism TAS Reactome
Metabolism of lipids TAS Reactome
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis TAS Reactome
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis IEA Reactome
PPARA activates gene expression TAS Reactome
Regulation of lipid metabolism by PPARalpha TAS Reactome
Respiratory Syncytial Virus Infection Pathway TAS Reactome
RNA Polymerase II Transcription TAS Reactome
RSV-host interactions TAS Reactome
Transcriptional regulation of white adipocyte differentiation TAS Reactome
Transcriptional regulation of white adipocyte differentiation IEA Reactome
Viral Infection Pathways TAS Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here