Gene description for TSHR
Gene name	thyroid stimulating hormone receptor
Gene symbol	TSHR
Other names/aliases	CHNG1 LGR3 hTSHR-I
Species	Homo sapiens
Database cross references - TSHR
ExoCarta	ExoCarta_7253
Vesiclepedia	VP_7253
Entrez Gene	7253
HGNC	12373
MIM	603372
UniProt	P16473
TSHR identified in sEVs derived from the following tissue/cell type
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927

Gene ontology annotations for TSHR

Molecular Function     thyroid-stimulating hormone receptor activity GO:0004996 IBA     thyroid-stimulating hormone receptor activity GO:0004996 IMP     protein binding GO:0005515 IPI     G protein-coupled peptide receptor activity GO:0008528 IBA     signaling receptor activity GO:0038023 IMP     protein-containing complex binding GO:0044877 IDA Biological Process     cell surface receptor signaling pathway GO:0007166 IMP     G protein-coupled receptor signaling pathway GO:0007186 TAS     G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger GO:0007187 TAS     adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0007189 IBA     adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0007189 IMP     cell-cell signaling GO:0007267 TAS     positive regulation of cell population proliferation GO:0008284 TAS     hormone-mediated signaling pathway GO:0009755 IBA     thyroid-stimulating hormone signaling pathway GO:0038194 IMP     positive regulation of cold-induced thermogenesis GO:0120162 ISS     cellular response to glycoprotein GO:1904588 IMP     cellular response to thyrotropin-releasing hormone GO:1905229 IMP Subcellular Localization     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 TAS     cell surface GO:0009986 ISS     basolateral plasma membrane GO:0016323 IDA     receptor complex GO:0043235 IDA