Gene description for Actb
Gene name actin, beta
Gene symbol Actb
Other names/aliases Actx
E430023M04Rik
beta-actin
Species Mus musculus
 Database cross references - Actb
ExoCarta ExoCarta_11461
Vesiclepedia VP_11461
Entrez Gene 11461
UniProt P60710  
 Actb identified in sEVs derived from the following tissue/cell type
Brain cancer cells 19109410    
Colon cancer cells 37309723    
Colorectal cancer cells 33431899    
Colorectal cancer cells 33431899    
Dendritic cells 10545503    
Embryonic fibroblasts 18494037    
Faeces 33431899    
Faeces 33431899    
Fibroblasts 23260141    
Macrophages 23658846    
Macrophages 23658846    
Macrophages 23658846    
Mast cells 11145662    
Mast cells 17486113    
Melanoma cells 34957415    
Melanoma cells 34957415    
Mov neuroglial cells 15210972    
Neural stem cells 25242146    
Neural stem cells 25242146    
Neural stem cells 25242146    
Oligodendrocytes 21136642    
Osteosarcoma cells 33785738    
Osteosarcoma cells 33785738    
Osteosarcoma cells 33785738    
Pancreatic cells 19351151    
T-cell lymphoma cells 37309723    
Tracheobronchial cells 19190083    
 Gene ontology annotations for Actb
Molecular Function
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IEA
    ATP hydrolysis activity GO:0016887 IEA
    ATP hydrolysis activity GO:0016887 ISO
    kinesin binding GO:0019894 IEA
    kinesin binding GO:0019894 ISO
    protein kinase binding GO:0019901 IBA
    protein kinase binding GO:0019901 IEA
    protein kinase binding GO:0019901 ISO
    Tat protein binding GO:0030957 IEA
    Tat protein binding GO:0030957 ISO
    identical protein binding GO:0042802 IEA
    identical protein binding GO:0042802 ISO
    nitric-oxide synthase binding GO:0050998 IEA
    nitric-oxide synthase binding GO:0050998 ISO
    structural constituent of postsynaptic actin cytoskeleton GO:0098973 IBA
    structural constituent of postsynaptic actin cytoskeleton GO:0098973 IEA
    structural constituent of postsynaptic actin cytoskeleton GO:0098973 ISO
Biological Process
    morphogenesis of a polarized epithelium GO:0001738 IEA
    morphogenesis of a polarized epithelium GO:0001738 ISO
    chromatin remodeling GO:0006338 NAS
    regulation of transcription by RNA polymerase II GO:0006357 NAS
    establishment or maintenance of cell polarity GO:0007163 IEA
    establishment or maintenance of cell polarity GO:0007163 ISO
    axonogenesis GO:0007409 IBA
    axonogenesis GO:0007409 ISO
    positive regulation of cell population proliferation GO:0008284 NAS
    regulation of transmembrane transporter activity GO:0022898 ISO
    regulation of mitotic metaphase/anaphase transition GO:0030071 NAS
    adherens junction assembly GO:0034333 IEA
    adherens junction assembly GO:0034333 ISO
    regulation of apoptotic process GO:0042981 NAS
    apical protein localization GO:0045176 IEA
    apical protein localization GO:0045176 ISO
    positive regulation of T cell differentiation GO:0045582 NAS
    negative regulation of cell differentiation GO:0045596 NAS
    positive regulation of cell differentiation GO:0045597 NAS
    positive regulation of myoblast differentiation GO:0045663 NAS
    positive regulation of DNA-templated transcription GO:0045893 NAS
    cell motility GO:0048870 IBA
    cell motility GO:0048870 IEA
    cell motility GO:0048870 ISO
    regulation of norepinephrine uptake GO:0051621 IEA
    regulation of norepinephrine uptake GO:0051621 ISO
    regulation of cell cycle GO:0051726 ISO
    regulation of G0 to G1 transition GO:0070316 NAS
    cellular response to electrical stimulus GO:0071257 ISO
    protein localization to adherens junction GO:0071896 IEA
    protein localization to adherens junction GO:0071896 ISO
    cellular response to cytochalasin B GO:0072749 IEA
    cellular response to cytochalasin B GO:0072749 ISO
    postsynaptic actin cytoskeleton organization GO:0098974 IEA
    postsynaptic actin cytoskeleton organization GO:0098974 ISO
    regulation of transepithelial transport GO:0150111 IEA
    regulation of transepithelial transport GO:0150111 ISO
    regulation of synaptic vesicle endocytosis GO:1900242 IDA
    regulation of synaptic vesicle endocytosis GO:1900242 IMP
    positive regulation of stem cell population maintenance GO:1902459 NAS
    regulation of protein localization to plasma membrane GO:1903076 IEA
    regulation of protein localization to plasma membrane GO:1903076 ISO
    positive regulation of double-strand break repair via homologous recombination GO:1905168 ISO
    regulation of G1/S transition of mitotic cell cycle GO:2000045 NAS
    regulation of double-strand break repair GO:2000779 NAS
    positive regulation of double-strand break repair GO:2000781 NAS
    regulation of nucleotide-excision repair GO:2000819 NAS
Subcellular Localization
    kinetochore GO:0000776 NAS
    chromatin GO:0000785 NAS
    nucleosome GO:0000786 ISO
    stress fiber GO:0001725 ISO
    podosome GO:0002102 ISO
    nucleus GO:0005634 IDA
    nucleus GO:0005634 ISO
    nucleus GO:0005634 ISS
    nucleoplasm GO:0005654 TAS
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    cytoplasm GO:0005737 ISO
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    cytoskeleton GO:0005856 IDA
    cytoskeleton GO:0005856 ISO
    actin filament GO:0005884 IBA
    plasma membrane GO:0005886 ISS
    brush border GO:0005903 IDA
    cell-cell junction GO:0005911 ISO
    adherens junction GO:0005912 IEA
    adherens junction GO:0005912 ISO
    focal adhesion GO:0005925 ISS
    actin cytoskeleton GO:0015629 IBA
    actin cytoskeleton GO:0015629 ISO
    actin cytoskeleton GO:0015629 ISS
    membrane GO:0016020 IBA
    nuclear matrix GO:0016363 NAS
    SWI/SNF complex GO:0016514 NAS
    RSC-type complex GO:0016586 NAS
    lamellipodium GO:0030027 IEA
    lamellipodium GO:0030027 ISO
    axon GO:0030424 IBA
    axon GO:0030424 ISO
    cortical cytoskeleton GO:0030863 IDA
    protein-containing complex GO:0032991 ISO
    protein-containing complex GO:0032991 ISS
    brahma complex GO:0035060 NAS
    NuA4 histone acetyltransferase complex GO:0035267 IBA
    NuA4 histone acetyltransferase complex GO:0035267 ISO
    cytoplasmic ribonucleoprotein granule GO:0036464 IEA
    cytoplasmic ribonucleoprotein granule GO:0036464 ISO
    myelin sheath GO:0043209 HDA
    apical junction complex GO:0043296 IEA
    apical junction complex GO:0043296 ISO
    calyx of Held GO:0044305 IDA
    calyx of Held GO:0044305 IMP
    membrane raft GO:0045121 ISO
    synapse GO:0045202 IBA
    tight junction GO:0070160 IEA
    tight junction GO:0070160 ISO
    npBAF complex GO:0071564 NAS
    nBAF complex GO:0071565 NAS
    dense body GO:0097433 ISS
    Schaffer collateral - CA1 synapse GO:0098685 IDA
    Schaffer collateral - CA1 synapse GO:0098685 IMP
    postsynaptic actin cytoskeleton GO:0098871 IEA
    postsynaptic actin cytoskeleton GO:0098871 ISO
    glutamatergic synapse GO:0098978 IEA
    glutamatergic synapse GO:0098978 ISO
    bBAF complex GO:0140092 NAS
    GBAF complex GO:0140288 NAS
    ribonucleoprotein complex GO:1990904 IEA
    ribonucleoprotein complex GO:1990904 ISO
 Experiment description of studies that identified Actb in sEVs
1
Experiment ID 26
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19109410    
Organism Mus musculus
Experiment description Proteomic and immunologic analyses of brain tumor exosomes.
Authors "Graner MW, Alzate O, Dechkovskaia AM, Keene JD, Sampson JH, Mitchell DA, Bigner DD"
Journal name FASEB
Publication year 2008
Sample Brain cancer cells
Sample name SMA560vIII
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.13-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
2
Experiment ID 907
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
3
Experiment ID 311
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 33431899    
Organism Mus musculus
Experiment description High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance
Authors "Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG."
Journal name Nat Commun
Publication year 2021
Sample Colorectal cancer cells
Sample name MC38
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
4
Experiment ID 312
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 33431899    
Organism Mus musculus
Experiment description High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance
Authors "Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG."
Journal name Nat Commun
Publication year 2021
Sample Colorectal cancer cells
Sample name MC38
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
5
Experiment ID 3
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 10545503    
Organism Mus musculus
Experiment description Molecular characterization of dendritic cell-derived exosomes. Selective accumulation of the heat shock protein hsc73.
Authors "Thery C, Regnault A, Garin J, Wolfers J, Zitvogel L, Ricciardi-Castagnoli P, Raposo G, Amigorena S."
Journal name JCB
Publication year 1999
Sample Dendritic cells
Sample name D1
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.20 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
6
Experiment ID 73
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 18494037    
Organism Mus musculus
Experiment description Difference gel electrophoresis analysis of Ras-transformed fibroblast cell-derived exosomes.
Authors "Ji H, Erfani N, Tauro BJ, Kapp EA, Zhu HJ, Moritz RL, Lim JW, Simpson RJ"
Journal name ELEC
Publication year 2008
Sample Embryonic fibroblasts
Sample name NIH3T3
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LCQ DECA]
Western blotting
7
Experiment ID 303
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 33431899    
Organism Mus musculus
Experiment description High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance
Authors "Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG."
Journal name Nat Commun
Publication year 2021
Sample Faeces
Sample name Intestinal epithelial cells - C57BL/6
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Lipid
miRNA
Methods used in the study Western blotting
Mass spectrometry
Immunofluorescence
miRNA array
HPLC
8
Experiment ID 303
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33431899    
Organism Mus musculus
Experiment description High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance
Authors "Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG."
Journal name Nat Commun
Publication year 2021
Sample Faeces
Sample name Intestinal epithelial cells - C57BL/6
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Lipid
miRNA
Methods used in the study Western blotting
Mass spectrometry
Immunofluorescence
miRNA array
HPLC
9
Experiment ID 304
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 33431899    
Organism Mus musculus
Experiment description High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance
Authors "Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG."
Journal name Nat Commun
Publication year 2021
Sample Faeces
Sample name Intestinal epithelial cells - C57BL/6
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Lipid
miRNA
Methods used in the study Western blotting
Mass spectrometry
Immunofluorescence
miRNA array
HPLC
10
Experiment ID 304
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33431899    
Organism Mus musculus
Experiment description High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance
Authors "Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG."
Journal name Nat Commun
Publication year 2021
Sample Faeces
Sample name Intestinal epithelial cells - C57BL/6
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Lipid
miRNA
Methods used in the study Western blotting
Mass spectrometry
Immunofluorescence
miRNA array
HPLC
11
Experiment ID 210
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors "Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL."
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 214
MISEV standards
✔ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23658846    
Organism Mus musculus
Experiment description Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis.
Authors "Hassani K, Olivier M."
Journal name PLoS Negl Trop Dis
Publication year 2013
Sample Macrophages
Sample name Leishmania-infected-Macrophage (J774A.1)
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Filtration
Protease inhibitors
Sucrose density gradient
Filtration
Ultracentrifugation
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 215
MISEV standards
✔ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23658846    
Organism Mus musculus
Experiment description Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis.
Authors "Hassani K, Olivier M."
Journal name PLoS Negl Trop Dis
Publication year 2013
Sample Macrophages
Sample name LPS-treated-Macrophage (J774A.1)
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Filtration
Protease inhibitors
Sucrose density gradient
Filtration
Ultracentrifugation
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 216
MISEV standards
✔ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23658846    
Organism Mus musculus
Experiment description Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis.
Authors "Hassani K, Olivier M."
Journal name PLoS Negl Trop Dis
Publication year 2013
Sample Macrophages
Sample name Normal-Macrophage (J774A.1)
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Filtration
Protease inhibitors
Sucrose density gradient
Filtration
Ultracentrifugation
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 5
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 11145662    
Organism Mus musculus
Experiment description Mast cell-dependent B and T lymphocyte activation is mediated by the secretion of immunologically active exosomes.
Authors "Skokos D, Le Panse S, Villa I, Rousselle JC, Peronet R, David B, Namane A, Mecheri S"
Journal name JIMMU
Publication year 2001
Sample Mast cells
Sample name P815
MC9
Bone marrow-derived mast cells
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF]
ELISA
16
Experiment ID 15
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
17
Experiment ID 15
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
18
Experiment ID 1117
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 34957415    
Organism Mus musculus
Experiment description Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism
Authors "García-Silva S, Benito-Martín A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÁ, Torres-Ruiz R, Rodríguez-Perales S, Martínez L, Pérez-Martínez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, Martínez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, Megías D, Mehrara BJ, Lyden D, Peinado H."
Journal name Nat Cancer
Publication year 2021
Sample Melanoma cells
Sample name B16-F1R2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 1118
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 34957415    
Organism Mus musculus
Experiment description Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism
Authors "García-Silva S, Benito-Martín A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÁ, Torres-Ruiz R, Rodríguez-Perales S, Martínez L, Pérez-Martínez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, Martínez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, Megías D, Mehrara BJ, Lyden D, Peinado H."
Journal name Nat Cancer
Publication year 2021
Sample Melanoma cells
Sample name B16-F1R2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 39
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15210972    
Organism Mus musculus
Experiment description Cells release prions in association with exosomes.
Authors "Fevrier B, Vilette D, Archer F, Loew D, Faigle W, Vidal M, Laude H, Raposo G"
Journal name PNAS
Publication year 2004
Sample Mov neuroglial cells
Sample name Mov neuroglial cell
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QSTAR]
Western blotting
Immunoelectron Microscopy
21
Experiment ID 262
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25242146    
Organism Mus musculus
Experiment description Extracellular Vesicles from Neural Stem Cells Transfer IFN-? via Ifngr1 to Activate Stat1 Signaling in Target Cells
Authors "Chiara Cossetti, Nunzio Iraci, Tim R. Mercer, Tommaso Leonardi, Emanuele Alpi, Denise Drago, Clara Alfaro-Cervello, Harpreet K. Saini, Matthew P. Davis, Julia Schaeffer, Beatriz Vega, Matilde Stefanini, CongJian Zhao, Werner Muller, Jose Manuel Garcia-Verdugo, Suresh Mathivanan, Angela Bachi, Anton J. Enright, John S. Mattick, Stefano Pluchino"
Journal name Molecular Cell
Publication year 2014
Sample Neural stem cells
Sample name NPCs
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.20 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
Microarray
22
Experiment ID 263
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25242146    
Organism Mus musculus
Experiment description Extracellular Vesicles from Neural Stem Cells Transfer IFN-? via Ifngr1 to Activate Stat1 Signaling in Target Cells
Authors "Chiara Cossetti, Nunzio Iraci, Tim R. Mercer, Tommaso Leonardi, Emanuele Alpi, Denise Drago, Clara Alfaro-Cervello, Harpreet K. Saini, Matthew P. Davis, Julia Schaeffer, Beatriz Vega, Matilde Stefanini, CongJian Zhao, Werner Muller, Jose Manuel Garcia-Verdugo, Suresh Mathivanan, Angela Bachi, Anton J. Enright, John S. Mattick, Stefano Pluchino"
Journal name Molecular Cell
Publication year 2014
Sample Neural stem cells
Sample name NPCs - Th1 treated
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.20 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 264
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25242146    
Organism Mus musculus
Experiment description Extracellular Vesicles from Neural Stem Cells Transfer IFN-? via Ifngr1 to Activate Stat1 Signaling in Target Cells
Authors "Chiara Cossetti, Nunzio Iraci, Tim R. Mercer, Tommaso Leonardi, Emanuele Alpi, Denise Drago, Clara Alfaro-Cervello, Harpreet K. Saini, Matthew P. Davis, Julia Schaeffer, Beatriz Vega, Matilde Stefanini, CongJian Zhao, Werner Muller, Jose Manuel Garcia-Verdugo, Suresh Mathivanan, Angela Bachi, Anton J. Enright, John S. Mattick, Stefano Pluchino"
Journal name Molecular Cell
Publication year 2014
Sample Neural stem cells
Sample name NPCs - Th2 treated
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.20 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
24
Experiment ID 33
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21136642    
Organism Mus musculus
Experiment description Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?
Authors "Kramer-Albers EM, Bretz N, Tenzer S, Winterstein C, Mobius W, Berger H, Nave KA, Schild H, Trotter J"
Journal name PROTEOMICS_CL
Publication year 2007
Sample Oligodendrocytes
Sample name Oligodendrocytes
Oli-neu
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
Immunoelectron Microscopy
25
Experiment ID 1321
MISEV standards
Biophysical techniques
✘ Enriched markers
✘ Negative markers
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 33785738    
Organism Homo sapiens
Experiment description Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs
Authors "Todkar K, Chikhi L, Desjardins V, El-Mortada F, Pépin G, Germain M. "
Journal name Nat Commun
Publication year 2021
Sample Osteosarcoma cells
Sample name U2OS
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
26
Experiment ID 1322
MISEV standards
Biophysical techniques
✘ Enriched markers
✘ Negative markers
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 33785738    
Organism Homo sapiens
Experiment description Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs
Authors "Todkar K, Chikhi L, Desjardins V, El-Mortada F, Pépin G, Germain M. "
Journal name Nat Commun
Publication year 2021
Sample Osteosarcoma cells
Sample name U2OS
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
27
Experiment ID 1323
MISEV standards
Biophysical techniques
✘ Enriched markers
✘ Negative markers
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 33785738    
Organism Homo sapiens
Experiment description Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs
Authors "Todkar K, Chikhi L, Desjardins V, El-Mortada F, Pépin G, Germain M. "
Journal name Nat Commun
Publication year 2021
Sample Osteosarcoma cells
Sample name U2OS
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
28
Experiment ID 188
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors "Lee HS, Jeong J, Lee KJ."
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
29
Experiment ID 908
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
30
Experiment ID 34
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19190083    
Organism Homo sapiens
Experiment description Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense.
Authors "Kesimer M, Scull M, Brighton B, Demaria G, Burns K, O'Neal W, Pickles RJ, Sheehan JK"
Journal name FASEB
Publication year 2009
Sample Tracheobronchial cells
Sample name Tracheobronchial epithelial cells
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density 1.16 -1.18 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study Mass spectrometry [QTOF]
Western blotting
Immunoelectron Microscopy
FACS
 Protein-protein interactions for Actb
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Rps3 27050
Co-fractionation Mus musculus
2 ABCG2 9429
Affinity Capture-MS Homo sapiens
3 MVP 9961
Affinity Capture-MS Homo sapiens
4 SRGAP1 57522
Affinity Capture-MS Homo sapiens
5 ACTR2 10097
Affinity Capture-MS Homo sapiens
6 ARHGAP21 57584
Affinity Capture-MS Homo sapiens
7 ABLIM1 3983
Affinity Capture-MS Homo sapiens
8 AP2B1 163
Affinity Capture-MS Homo sapiens
9 Pknox1  
Affinity Capture-MS Mus musculus
10 IMMT 10989
Affinity Capture-MS Homo sapiens
11 CCT3 7203
Affinity Capture-MS Homo sapiens
12 RAB1A 5861
Affinity Capture-MS Homo sapiens
13 AAK1 22848
Affinity Capture-MS Homo sapiens
14 VAPA 9218
Affinity Capture-MS Homo sapiens
15 Inadl  
Affinity Capture-MS Mus musculus
16 CPM 1368
Affinity Capture-MS Homo sapiens
17 ARPC2 10109
Affinity Capture-MS Homo sapiens
18 KCTD10 83892
Affinity Capture-MS Homo sapiens
19 CLTA 1211
Affinity Capture-MS Homo sapiens
20 Cotl1 72042
Two-hybrid Mus musculus
Reconstituted Complex Mus musculus
21 TPM2 7169
Affinity Capture-MS Homo sapiens
22 CAP1 10487
Affinity Capture-MS Homo sapiens
23 Ybx1 22608
Co-fractionation Mus musculus
24 AFAP1 60312
Affinity Capture-MS Homo sapiens
25 DBN1 1627
Affinity Capture-MS Homo sapiens
26 LIMA1 51474
Affinity Capture-MS Homo sapiens
27 EPS15 2060
Affinity Capture-MS Homo sapiens
28 INF2 64423
Affinity Capture-MS Homo sapiens
29 LGALS1 3956
Affinity Capture-MS Homo sapiens
30 SRGAP2 23380
Affinity Capture-MS Homo sapiens
31 CCT4 10575
Affinity Capture-MS Homo sapiens
32 BASP1 10409
Affinity Capture-MS Homo sapiens
33 Rps6 20104
Co-fractionation Mus musculus
34 Mks1  
Affinity Capture-MS Mus musculus
35 RAB14 51552
Affinity Capture-MS Homo sapiens
36 CFL1 1072
Two-hybrid Homo sapiens
37 CLTB 1212
Affinity Capture-MS Homo sapiens
38 RPL22 6146
Affinity Capture-MS Homo sapiens
39 Tmem173  
Proximity Label-MS Mus musculus
40 CAPZB 832
Affinity Capture-MS Homo sapiens
41 Cyfip1 20430
Affinity Capture-MS Mus musculus
42 PPP1R12A 4659
Affinity Capture-MS Homo sapiens
43 Ywhab 54401
Co-fractionation Mus musculus
44 COL5A1 1289
Affinity Capture-MS Homo sapiens
45 MYO5B 4645
Affinity Capture-MS Homo sapiens
46 DCTN4 51164
Affinity Capture-MS Homo sapiens
47 ACTR3 10096
Affinity Capture-MS Homo sapiens
48 AP2A1 160
Affinity Capture-MS Homo sapiens
49 TRMT112 51504
Affinity Capture-MS Homo sapiens
50 Invs  
Affinity Capture-MS Mus musculus
51 PPP1R18 170954
Affinity Capture-MS Homo sapiens
52 Rpl26 19941
Co-fractionation Mus musculus
53 STOM 2040
Affinity Capture-MS Homo sapiens
54 CD109 135228
Affinity Capture-MS Homo sapiens
55 ERC1 23085
Affinity Capture-MS Homo sapiens
56 SPECC1L 23384
Affinity Capture-MS Homo sapiens
57 Tagln2 21346
Co-fractionation Mus musculus
58 CHCHD3 54927
Affinity Capture-MS Homo sapiens
59 PHLDB2 90102
Affinity Capture-MS Homo sapiens
60 Set 56086
Affinity Capture-MS Mus musculus
61 RALA 5898
Affinity Capture-MS Homo sapiens
62 CEP162  
Affinity Capture-MS Homo sapiens
63 MYO1B 4430
Affinity Capture-MS Homo sapiens
64 TMOD1  
Affinity Capture-MS Homo sapiens
65 SRI 6717
Affinity Capture-MS Homo sapiens
66 Lipc  
Affinity Capture-MS Mus musculus
67 TPRN 286262
Affinity Capture-MS Homo sapiens
68 Eed  
Affinity Capture-MS Mus musculus
69 ZNF598 90850
Affinity Capture-MS Homo sapiens
70 GTSE1 51512
Affinity Capture-MS Homo sapiens
71 ARPC5L 81873
Affinity Capture-MS Homo sapiens
72 Pde4dip  
Affinity Capture-MS Mus musculus
73 PLS3 5358
Affinity Capture-MS Homo sapiens
74 CYBRD1 79901
Affinity Capture-MS Homo sapiens
75 TES 26136
Affinity Capture-MS Homo sapiens
76 Rps4x 20102
Co-fractionation Mus musculus
77 STAMBPL1  
Affinity Capture-MS Homo sapiens
78 Rac1 19353
Co-fractionation Mus musculus
79 COBL  
Affinity Capture-MS Homo sapiens
80 STOML2 30968
Affinity Capture-MS Homo sapiens
81 PFN1 5216
Affinity Capture-MS Homo sapiens
82 PPP1CA 5499
Affinity Capture-MS Homo sapiens
83 NOLC1 9221
Affinity Capture-MS Homo sapiens
84 CPNE2 221184
Two-hybrid Homo sapiens
85 TCP1 6950
Affinity Capture-MS Homo sapiens
86 KIAA1211  
Affinity Capture-MS Homo sapiens
87 Tfe3  
Affinity Capture-MS Mus musculus
88 EFHD2 79180
Affinity Capture-MS Homo sapiens
89 CAPZA1 829
Affinity Capture-MS Homo sapiens
90 NCKIPSD 51517
Affinity Capture-MS Homo sapiens
91 PSMD4 5710
Affinity Capture-MS Homo sapiens
92 SORBS2  
Affinity Capture-MS Homo sapiens
93 LUZP1 7798
Affinity Capture-MS Homo sapiens
94 Kcnma1  
Affinity Capture-MS Mus musculus
95 SIPA1L1 26037
Affinity Capture-MS Homo sapiens
96 Mt3  
Affinity Capture-MS Mus musculus
97 GNAI1 2770
Affinity Capture-MS Homo sapiens
98 CLTCL1 8218
Affinity Capture-MS Homo sapiens
99 ALPI  
Affinity Capture-MS Homo sapiens
100 RRAS2 22800
Affinity Capture-MS Homo sapiens
101 LRRFIP2 9209
Affinity Capture-MS Homo sapiens
102 SNX33 257364
Affinity Capture-MS Homo sapiens
103 CHMP4B 128866
Affinity Capture-MS Homo sapiens
104 LRRFIP1 9208
Affinity Capture-MS Homo sapiens
105 ACTN4 81
Affinity Capture-MS Homo sapiens
106 MYO10 4651
Affinity Capture-MS Homo sapiens
107 ARHGAP11A  
Affinity Capture-MS Homo sapiens
108 FLNB 2317
Affinity Capture-MS Homo sapiens
109 BMP2K 55589
Affinity Capture-MS Homo sapiens
110 Tpt1 22070
Co-fractionation Mus musculus
111 GNAI2 2771
Affinity Capture-MS Homo sapiens
112 ARPC5 10092
Affinity Capture-MS Homo sapiens
113 PIK3C2A 5286
Affinity Capture-MS Homo sapiens
114 STON2 85439
Affinity Capture-MS Homo sapiens
115 Ahi1  
Affinity Capture-MS Mus musculus
116 ACTR10 55860
Affinity Capture-MS Homo sapiens
117 FLOT2 2319
Affinity Capture-MS Homo sapiens
118 PICALM 8301
Affinity Capture-MS Homo sapiens
119 ARPC1A 10552
Affinity Capture-MS Homo sapiens
120 ACTG1 71
Affinity Capture-MS Homo sapiens
121 ST5 6764
Affinity Capture-MS Homo sapiens
122 GPRC5A 9052
Affinity Capture-MS Homo sapiens
123 CPNE4 131034
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
124 PPP1R12B 4660
Affinity Capture-MS Homo sapiens
125 MAT2A 4144
Affinity Capture-MS Homo sapiens
126 DST 667
Affinity Capture-MS Homo sapiens
127 CSNK1G3 1456
Affinity Capture-MS Homo sapiens
128 GTF3C3 9330
Affinity Capture-MS Homo sapiens
129 CLINT1 9685
Affinity Capture-MS Homo sapiens
130 Pfn2  
Affinity Capture-MS Mus musculus
Reconstituted Complex Mus musculus
131 ARPC1B 10095
Affinity Capture-MS Homo sapiens
132 UBAP2 55833
Affinity Capture-MS Homo sapiens
133 Prom1  
Affinity Capture-Western Mus musculus
134 Rps8 20116
Co-fractionation Mus musculus
135 LMO7 4008
Affinity Capture-MS Homo sapiens
136 AHNAK 79026
Affinity Capture-MS Homo sapiens
137 Rps28 54127
Co-fractionation Mus musculus
138 TJP1 7082
Affinity Capture-MS Homo sapiens
139 ACTBL2 345651
Affinity Capture-MS Homo sapiens
140 CTTN 2017
Affinity Capture-MS Homo sapiens
141 SPECC1 92521
Affinity Capture-MS Homo sapiens
142 MYO5A 4644
Affinity Capture-MS Homo sapiens
143 MYO19  
Affinity Capture-MS Homo sapiens
144 MYL6B 140465
Affinity Capture-MS Homo sapiens
145 Wasf3  
Co-fractionation Mus musculus
146 HIP1R 9026
Affinity Capture-MS Homo sapiens
147 MYO5C 55930
Affinity Capture-MS Homo sapiens
148 MYO1C 4641
Affinity Capture-MS Homo sapiens
149 Rpl22 19934
Co-fractionation Mus musculus
150 AP2M1 1173
Affinity Capture-MS Homo sapiens
151 RAI14 26064
Affinity Capture-MS Homo sapiens
152 Nphp4  
Affinity Capture-MS Mus musculus
153 GNA11 2767
Affinity Capture-MS Homo sapiens
154 TPM1 7168
Affinity Capture-MS Homo sapiens
155 Traf6  
Affinity Capture-MS Mus musculus
Affinity Capture-Western Mus musculus
156 CORO2A  
Affinity Capture-MS Homo sapiens
157 Ipo9  
Affinity Capture-Western Mus musculus
158 TJP2 9414
Affinity Capture-MS Homo sapiens
159 MYO6 4646
Affinity Capture-MS Homo sapiens
160 FCHO2 115548
Affinity Capture-MS Homo sapiens
161 Usp25 30940
Affinity Capture-MS Mus musculus
162 Dmrt2  
Affinity Capture-MS Mus musculus
163 SEC16A 9919
Affinity Capture-MS Homo sapiens
164 Syncrip 56403
Co-fractionation Mus musculus
165 TMOD3 29766
Affinity Capture-MS Homo sapiens
166 AP2A2 161
Affinity Capture-MS Homo sapiens
167 Rps3a1 20091
Co-fractionation Mus musculus
168 Atp6v1a 11964
Affinity Capture-Western Mus musculus
169 CGN  
Affinity Capture-MS Homo sapiens
170 FLII 2314
Affinity Capture-MS Homo sapiens
171 TWF1 5756
Affinity Capture-MS Homo sapiens
172 AKAP2 11217
Affinity Capture-MS Homo sapiens
173 CLTC 1213
Affinity Capture-MS Homo sapiens
174 MPRIP 23164
Affinity Capture-MS Homo sapiens
175 KIDINS220 57498
Affinity Capture-MS Homo sapiens
176 LIMCH1 22998
Affinity Capture-MS Homo sapiens
177 TRIOBP 11078
Affinity Capture-MS Homo sapiens
178 TPM4 7171
Affinity Capture-MS Homo sapiens
179 TWF2 11344
Affinity Capture-MS Homo sapiens
180 FLOT1 10211
Affinity Capture-MS Homo sapiens
181 Park2  
Affinity Capture-Western Mus musculus
182 Fancd2  
Affinity Capture-MS Mus musculus
183 TPM3 7170
Affinity Capture-MS Homo sapiens
184 SPTBN1 6711
Affinity Capture-MS Homo sapiens
185 Rps27a 78294
Co-fractionation Mus musculus
186 GSN 2934
Affinity Capture-MS Homo sapiens
187 SEC24B 10427
Affinity Capture-MS Homo sapiens
188 ARPC3 10094
Affinity Capture-MS Homo sapiens
189 SNCA 6622
Affinity Capture-MS Homo sapiens
190 NEXN 91624
Affinity Capture-MS Homo sapiens
191 SPTAN1 6709
Affinity Capture-MS Homo sapiens
192 CLIC1 1192
Affinity Capture-MS Homo sapiens
193 CCT8 10694
Affinity Capture-MS Homo sapiens
194 DAB2 1601
Affinity Capture-MS Homo sapiens
195 KIAA0753  
Affinity Capture-MS Homo sapiens
196 SVIL 6840
Affinity Capture-MS Homo sapiens
197 CDC42 998
Affinity Capture-MS Homo sapiens
198 SIPA1 6494
Affinity Capture-MS Homo sapiens
199 RUVBL2 10856
Affinity Capture-MS Homo sapiens
200 Ube2i  
Two-hybrid Mus musculus
201 MISP 126353
Affinity Capture-MS Homo sapiens
202 XPR1 9213
Affinity Capture-MS Homo sapiens
203 SIPA1L3  
Affinity Capture-MS Homo sapiens
204 Kctd13  
Affinity Capture-MS Mus musculus
205 CAPZA2 830
Affinity Capture-MS Homo sapiens
206 Pfn1 18643
Affinity Capture-MS Mus musculus
Two-hybrid Mus musculus
207 DCTN2 10540
Affinity Capture-MS Homo sapiens
208 CAP2 10486
Affinity Capture-MS Homo sapiens
209 ITPR3 3710
Affinity Capture-MS Homo sapiens
210 EIF4ENIF1 56478
Two-hybrid Homo sapiens
211 Iqcb1  
Affinity Capture-MS Mus musculus
212 Unk  
Affinity Capture-RNA Mus musculus
213 CPNE1 8904
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
214 OXR1  
Affinity Capture-MS Homo sapiens
215 UNC45A 55898
Affinity Capture-MS Homo sapiens
216 ACTA1 58
Affinity Capture-MS Homo sapiens
217 RUVBL1 8607
Affinity Capture-MS Homo sapiens
218 LRCH3 84859
Affinity Capture-MS Homo sapiens
219 MICAL3 57553
Affinity Capture-MS Homo sapiens
220 Syn2  
Co-fractionation Mus musculus
221 SYNPO 11346
Affinity Capture-MS Homo sapiens
222 DAPK3 1613
Affinity Capture-MS Homo sapiens
223 FLNA 2316
Affinity Capture-MS Homo sapiens
224 Rps14 20044
Co-fractionation Mus musculus
225 GNAS 2778
Affinity Capture-MS Homo sapiens
226 MYO1E 4643
Affinity Capture-MS Homo sapiens
227 DOCK7 85440
Affinity Capture-MS Homo sapiens
228 Rnf2  
Affinity Capture-MS Mus musculus
229 Tubb5 22154
Co-fractionation Mus musculus
230 RAB5C 5878
Affinity Capture-MS Homo sapiens
231 GAS2L1 10634
Affinity Capture-MS Homo sapiens
232 Nphp1  
Affinity Capture-MS Mus musculus
233 MYO18A 399687
Affinity Capture-MS Homo sapiens
234 DSG2 1829
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which Actb is involved
PathwayEvidenceSource
Adherens junctions interactions IEA Reactome
Axon guidance IEA Reactome
B-WICH complex positively regulates rRNA expression IEA Reactome
Cell junction organization IEA Reactome
Cell-Cell communication IEA Reactome
Cell-cell junction organization IEA Reactome
Cell-extracellular matrix interactions IEA Reactome
Clathrin-mediated endocytosis IEA Reactome
Deubiquitination IEA Reactome
Developmental Biology IEA Reactome
DNA Damage Recognition in GG-NER IEA Reactome
DNA Repair IEA Reactome
EPH-Ephrin signaling IEA Reactome
EPHB-mediated forward signaling IEA Reactome
Epigenetic regulation of gene expression IEA Reactome
Fcgamma receptor (FCGR) dependent phagocytosis IEA Reactome
Formation of annular gap junctions IEA Reactome
Gap junction degradation IEA Reactome
Gap junction trafficking IEA Reactome
Gap junction trafficking and regulation IEA Reactome
Gene expression (Transcription) IEA Reactome
Global Genome Nucleotide Excision Repair (GG-NER) IEA Reactome
Immune System IEA Reactome
Innate Immune System IEA Reactome
Interaction between L1 and Ankyrins IEA Reactome
L1CAM interactions IEA Reactome
MAP2K and MAPK activation IEA Reactome
MAPK family signaling cascades IEA Reactome
MAPK1/MAPK3 signaling IEA Reactome
Membrane Trafficking IEA Reactome
Metabolism of proteins IEA Reactome
Nervous system development IEA Reactome
Nucleotide Excision Repair IEA Reactome
Positive epigenetic regulation of rRNA expression IEA Reactome
Post-translational protein modification IEA Reactome
RAF/MAP kinase cascade IEA Reactome
Recycling pathway of L1 IEA Reactome
Regulation of actin dynamics for phagocytic cup formation IEA Reactome
RHO GTPase cycle IEA Reactome
RHO GTPase Effectors IEA Reactome
RHO GTPases Activate Formins IEA Reactome
RHO GTPases activate IQGAPs IEA Reactome
RHO GTPases Activate WASPs and WAVEs IEA Reactome
RHOF GTPase cycle IEA Reactome
Signal Transduction IEA Reactome
Signaling by Receptor Tyrosine Kinases IEA Reactome
Signaling by Rho GTPases IEA Reactome
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 IEA Reactome
Signaling by VEGF IEA Reactome
UCH proteinases IEA Reactome
VEGFA-VEGFR2 Pathway IEA Reactome
Vesicle-mediated transport IEA Reactome





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