Experiment description of studies that identified IBTK in sEVs

1 Experiment ID 236 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name MHCC97L Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

Protein-protein interactions for IBTK

Protein Interactor ExoCarta ID Identification method PubMed Species 1 ESPL1   Affinity Capture-MS Homo sapiens 2 HECTD1 25831 Affinity Capture-MS Homo sapiens 3 POP7   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 4 ISG15 9636 Affinity Capture-MS Homo sapiens 5 FBXL6   Proximity Label-MS Homo sapiens 6 FTSJ1 24140 Affinity Capture-MS Homo sapiens 7 Sars 20226 Affinity Capture-MS Mus musculus 8 RPS3 6188 Affinity Capture-MS Homo sapiens 9 RPL10 6134 Affinity Capture-MS Homo sapiens 10 Ruvbl1 56505 Affinity Capture-MS Mus musculus 11 PRKCD 5580 Affinity Capture-Western Homo sapiens 12 KIF14 9928 Affinity Capture-MS Homo sapiens 13 RPL6 6128 Affinity Capture-MS Homo sapiens 14 RPS8 6202 Affinity Capture-MS Homo sapiens 15 EGLN3   Affinity Capture-MS Homo sapiens 16 RPP25L   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 17 DDX21 9188 Affinity Capture-MS Homo sapiens 18 MSL1 339287 Affinity Capture-MS Homo sapiens 19 NAT10 55226 Affinity Capture-MS Homo sapiens 20 PPP1CA 5499 Two-hybrid Homo sapiens 21 RPS9 6203 Affinity Capture-MS Homo sapiens 22 NOP56 10528 Affinity Capture-MS Homo sapiens 23 MIB1 57534 Proximity Label-MS Homo sapiens 24 TSR1 55720 Affinity Capture-MS Homo sapiens 25 CUL3 8452 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens 26 RGS2   Affinity Capture-MS Homo sapiens 27 USP10 9100 Affinity Capture-MS Homo sapiens 28 RPS27 6232 Affinity Capture-MS Homo sapiens 29 PRKD1 5587 Biochemical Activity Homo sapiens Affinity Capture-Western Homo sapiens 30 RFC3 5983 Affinity Capture-MS Homo sapiens 31 EIF4A1 1973 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 32 Clasp2   Affinity Capture-MS Mus musculus 33 MAPRE3   Proximity Label-MS Homo sapiens 34 TTK 7272 Affinity Capture-MS Homo sapiens 35 SRP72 6731 Affinity Capture-MS Homo sapiens 36 DOT1L 84444 Affinity Capture-MS Homo sapiens 37 RFC1 5981 Affinity Capture-MS Homo sapiens 38 PRKCG 5582 Affinity Capture-Western Homo sapiens 39 DPPA4   Affinity Capture-MS Homo sapiens 40 Ezr 22350 Affinity Capture-MS Mus musculus 41 FKBP5 2289 Affinity Capture-MS Homo sapiens 42 RPS20 6224 Proximity Label-MS Homo sapiens 43 GSK3B 2932 Affinity Capture-Western Homo sapiens 44 CNOT1 23019 Affinity Capture-MS Homo sapiens 45 SERBP1 26135 Proximity Label-MS Homo sapiens 46 DHX30 22907 Affinity Capture-MS Homo sapiens 47 PRKCA 5578 Affinity Capture-Western Homo sapiens 48 WDR74 54663 Affinity Capture-MS Homo sapiens 49 Rrbp1   Affinity Capture-MS Mus musculus 50 DCTN1 1639 Proximity Label-MS Homo sapiens 51 RPLP1 6176 Affinity Capture-MS Homo sapiens 52 BICD2 23299 Proximity Label-MS Homo sapiens 53 PCGF1 84759 Affinity Capture-MS Homo sapiens 54 PTGES3 10728 Affinity Capture-MS Homo sapiens 55 MFN2 9927 Proximity Label-MS Homo sapiens 56 RFC4 5984 Affinity Capture-MS Homo sapiens 57 ITK 3702 Affinity Capture-Western Homo sapiens 58 POU5F1   Affinity Capture-MS Homo sapiens 59 BTK 695 Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens 60 PRKCB 5579 Biochemical Activity Homo sapiens Affinity Capture-Western Homo sapiens 61 RPLP0 6175 Affinity Capture-MS Homo sapiens 62 AKT1 207 Affinity Capture-Western Homo sapiens 63 NANOG   Affinity Capture-MS Homo sapiens 64 Eif3e 16341 Affinity Capture-MS Mus musculus 65 PLCG1 5335 Affinity Capture-Western Homo sapiens 66 RPA3 6119 Proximity Label-MS Homo sapiens 67 LAMTOR3 8649 Two-hybrid Homo sapiens 68 NELFE 7936 Affinity Capture-MS Homo sapiens 69 PRKCE 5581 Affinity Capture-Western Homo sapiens 70 LACTB 114294 Affinity Capture-MS Homo sapiens 71 BCOR   Affinity Capture-MS Homo sapiens View the network

Pathways in which IBTK is involved

No pathways found