Gene description for Uggt1
Gene name UDP-glucose glycoprotein glucosyltransferase 1
Gene symbol Uggt1
Other names/aliases 0910001L17Rik
A930007H10Rik
AA589501
AI414429
AI448372
C820010P03Rik
GT
UGT1
Ugcgl1
Species Mus musculus
 Database cross references - Uggt1
ExoCarta ExoCarta_320011
Vesiclepedia VP_320011
Entrez Gene 320011
UniProt Q6P5E4  
 Uggt1 identified in sEVs derived from the following tissue/cell type
Neural stem cells 25242146    
Pancreatic cells 19351151    
 Gene ontology annotations for Uggt1
Molecular Function
    UDP-glucose:glycoprotein glucosyltransferase activity GO:0003980 IBA
    UDP-glucose:glycoprotein glucosyltransferase activity GO:0003980 ISO
    UDP-glucose:glycoprotein glucosyltransferase activity GO:0003980 ISS
    protein binding GO:0005515 IPI
    unfolded protein binding GO:0051082 IBA
    unfolded protein binding GO:0051082 ISO
    unfolded protein binding GO:0051082 ISS
Biological Process
    protein glycosylation GO:0006486 IEA
    protein N-linked glycosylation via asparagine GO:0018279 IBA
    ERAD pathway GO:0036503 IBA
    UDP-glucosylation GO:0097359 IEA
Subcellular Localization
    endoplasmic reticulum GO:0005783 IBA
    endoplasmic reticulum GO:0005783 ISO
    endoplasmic reticulum lumen GO:0005788 ISO
    endoplasmic reticulum lumen GO:0005788 ISS
    endoplasmic reticulum-Golgi intermediate compartment GO:0005793 ISO
    endoplasmic reticulum-Golgi intermediate compartment GO:0005793 ISS
    protein-containing complex GO:0032991 IEA
    protein-containing complex GO:0032991 ISO
 Experiment description of studies that identified Uggt1 in sEVs
1
Experiment ID 264
MISEV standards
Biophysical techniques
CD63|CD9
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25242146    
Organism Mus musculus
Experiment description Extracellular Vesicles from Neural Stem Cells Transfer IFN-? via Ifngr1 to Activate Stat1 Signaling in Target Cells
Authors "Chiara Cossetti, Nunzio Iraci, Tim R. Mercer, Tommaso Leonardi, Emanuele Alpi, Denise Drago, Clara Alfaro-Cervello, Harpreet K. Saini, Matthew P. Davis, Julia Schaeffer, Beatriz Vega, Matilde Stefanini, CongJian Zhao, Werner Muller, Jose Manuel Garcia-Verdugo, Suresh Mathivanan, Angela Bachi, Anton J. Enright, John S. Mattick, Stefano Pluchino"
Journal name Molecular Cell
Publication year 2014
Sample Neural stem cells
Sample name NPCs - Th2 treated
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.20 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 188
MISEV standards
EM
Biophysical techniques
GAPDH|UCHL1|HSP90
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors "Lee HS, Jeong J, Lee KJ."
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Uggt1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Acbd3  
Co-fractionation Mus musculus
2 Rps23 66475
Co-fractionation Mus musculus
3 Rpl14 67115
Co-fractionation Mus musculus
4 Rpl23 65019
Co-fractionation Mus musculus
5 Sep15  
Co-fractionation Mus musculus
6 Endod1  
Co-fractionation Mus musculus
7 Rpl3 27367
Co-fractionation Mus musculus
8 Nsun2 28114
Co-fractionation Mus musculus
9 Sdf2  
Co-fractionation Mus musculus
10 Eed  
Affinity Capture-MS Mus musculus
11 Serpina1c  
Co-fractionation Mus musculus
12 Rpl13a 22121
Co-fractionation Mus musculus
13 Capn1 12333
Co-fractionation Mus musculus
14 Glg1 20340
Co-fractionation Mus musculus
15 Mesdc2  
Co-fractionation Mus musculus
16 Vti1a 53611
Co-fractionation Mus musculus
17 Os9  
Co-fractionation Mus musculus
18 Timm8b  
Co-fractionation Mus musculus
19 Fancd2  
Affinity Capture-MS Mus musculus
20 Rps2 16898
Co-fractionation Mus musculus
21 Lipc  
Affinity Capture-MS Mus musculus
View the network image/svg+xml
 Pathways in which Uggt1 is involved
No pathways found





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