Gene description for Aldoc
Gene name aldolase C, fructose-bisphosphate
Gene symbol Aldoc
Other names/aliases AI847350
AU040929
Aldo3
Scrg2
Species Mus musculus
 Database cross references - Aldoc
ExoCarta ExoCarta_11676
Entrez Gene 11676
UniProt P05063  
 Aldoc identified in exosomes derived from the following tissue/cell type
Neural stem cells 25242146    
 Gene ontology annotations for Aldoc
Molecular Function
    cytoskeletal protein binding GO:0008092 ISO
    lyase activity GO:0016829 IEA
    catalytic activity GO:0003824 IEA
    fructose-bisphosphate aldolase activity GO:0004332 NAS
Biological Process
    fructose 1,6-bisphosphate metabolic process GO:0030388 ISO
    glycolytic process GO:0006096 IEA
    aging GO:0007568 ISO
    protein homotetramerization GO:0051289 ISO
    protein heterotetramerization GO:0051290 ISO
    apoptotic process GO:0006915 ISO
Subcellular Localization
    mitochondrion GO:0005739 IDA
    extracellular exosome GO:0070062 ISO
    cytoplasm GO:0005737 ISO
    axon GO:0030424 ISO
 Experiment description of studies that identified Aldoc in exosomes
1
Experiment ID 264
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
CD63|CD9
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25242146    
Organism Mus musculus
Experiment description Extracellular Vesicles from Neural Stem Cells Transfer IFN-γ via Ifngr1 to Activate Stat1 Signaling in Target Cells
Authors Chiara Cossetti, Nunzio Iraci, Tim R. Mercer, Tommaso Leonardi, Emanuele Alpi, Denise Drago, Clara Alfaro-Cervello, Harpreet K. Saini, Matthew P. Davis, Julia Schaeffer, Beatriz Vega, Matilde Stefanini, CongJian Zhao, Werner Muller, Jose Manuel Garcia-Verdugo, Suresh Mathivanan, Angela Bachi, Anton J. Enright, John S. Mattick, Stefano Pluchino
Journal name Molecular Cell
Publication year 2014
Sample Neural stem cells
Sample name NPCs - Th2 treated
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.20 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Aldoc
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Aldoc is involved
PathwayEvidenceSource
Gluconeogenesis IEA Reactome
Glycolysis IEA Reactome





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