Gene description for C10orf90
Gene name chromosome 10 open reading frame 90
Gene symbol C10orf90
Other names/aliases FATS
bA422P15.2
Species Homo sapiens
 Database cross references - C10orf90
ExoCarta ExoCarta_118611
Vesiclepedia VP_118611
Entrez Gene 118611
HGNC 26563
UniProt Q96M02  
 C10orf90 identified in sEVs derived from the following tissue/cell type
Urine 21595033    
Urine 21595033    
Urine 21595033    
 Gene ontology annotations for C10orf90
Molecular Function
    ubiquitin protein ligase activity GO:0061630 ISS
Biological Process
    protein polyubiquitination GO:0000209 ISS
    protein ubiquitination GO:0016567 ISS
    regulation of centriole replication GO:0046599 IBA
    protein stabilization GO:0050821 ISS
Subcellular Localization
    cytoplasm GO:0005737 IDA
    centrosome GO:0005813 IBA
    centrosome GO:0005813 IDA
    centriole GO:0005814 IBA
    cytosol GO:0005829 IBA
    cytosol GO:0005829 IDA
    plasma membrane GO:0005886 IDA
    actin cytoskeleton GO:0015629 IDA
 Experiment description of studies that identified C10orf90 in sEVs
1
Experiment ID 193
MISEV standards
EM
Biophysical techniques
CD63|CD9
Enriched markers
PHB
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 194
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of basement membrane nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 195
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of early IgA nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for C10orf90
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GPR150  
Affinity Capture-MS Homo sapiens
2 PDLIM7 9260
Affinity Capture-MS Homo sapiens
3 FASN 2194
Positive Genetic Homo sapiens
4 MTNR1A  
Two-hybrid Homo sapiens
5 UBC 7316
Affinity Capture-MS Homo sapiens
6 GSK3B 2932
Two-hybrid Homo sapiens
7 TP53 7157
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
View the network image/svg+xml
 Pathways in which C10orf90 is involved
No pathways found





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