Gene description for Atp6v0d1
Gene name ATPase, H+ transporting, lysosomal V0 subunit D1
Gene symbol Atp6v0d1
Other names/aliases AI267038
Ac39
Atp6d
P39
VATX
Vma6
Species Mus musculus
 Database cross references - Atp6v0d1
ExoCarta ExoCarta_11972
Vesiclepedia VP_11972
Entrez Gene 11972
UniProt P51863  
 Atp6v0d1 identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Atp6v0d1
Molecular Function
    protein binding GO:0005515 IPI
    protein-containing complex binding GO:0044877 IEA
    protein-containing complex binding GO:0044877 ISO
    proton-transporting ATPase activity, rotational mechanism GO:0046961 IDA
Biological Process
    intracellular iron ion homeostasis GO:0006879 ISO
    intracellular iron ion homeostasis GO:0006879 ISS
    vacuolar transport GO:0007034 IBA
    vacuolar acidification GO:0007035 IBA
    cellular response to increased oxygen levels GO:0036295 ISO
    cellular response to increased oxygen levels GO:0036295 ISS
    cilium assembly GO:0060271 ISS
    synaptic vesicle lumen acidification GO:0097401 EXP
    synaptic vesicle lumen acidification GO:0097401 IDA
    synaptic vesicle lumen acidification GO:0097401 IMP
Subcellular Localization
    vacuolar proton-transporting V-type ATPase, V0 domain GO:0000220 ISS
    lysosomal membrane GO:0005765 IEA
    early endosome GO:0005769 IBA
    early endosome GO:0005769 IDA
    centrosome GO:0005813 ISO
    centrosome GO:0005813 ISS
    synaptic vesicle GO:0008021 ISO
    membrane GO:0016020 ISO
    apical plasma membrane GO:0016324 IEA
    apical plasma membrane GO:0016324 ISO
    vacuolar proton-transporting V-type ATPase complex GO:0016471 IBA
    vacuolar proton-transporting V-type ATPase complex GO:0016471 ISO
    clathrin-coated vesicle membrane GO:0030665 IEA
    synaptic vesicle membrane GO:0030672 IEA
    synaptic vesicle membrane GO:0030672 ISO
    protein-containing complex GO:0032991 ISO
    proton-transporting V-type ATPase complex GO:0033176 IDA
    proton-transporting V-type ATPase, V0 domain GO:0033179 IDA
    plasma membrane proton-transporting V-type ATPase complex GO:0033181 IBA
    axon terminus GO:0043679 IEA
    axon terminus GO:0043679 ISO
 Experiment description of studies that identified Atp6v0d1 in exosomes
1
Experiment ID 188
MISEV standards
EM
Biophysical techniques
GAPDH|UCHL1|HSP90
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Atp6v0d1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Vamp2  
Affinity Capture-MS Mus musculus
2 SNCA 6622
Affinity Capture-MS Homo sapiens
3 Eed  
Affinity Capture-MS Mus musculus
4 Tfe3  
Affinity Capture-MS Mus musculus
5 Atg5  
Affinity Capture-MS Mus musculus
6 Snap25 20614
Affinity Capture-MS Mus musculus
7 HSD17B10 3028
Affinity Capture-MS Homo sapiens
8 Kctd13  
Affinity Capture-MS Mus musculus
9 Kcnma1  
Affinity Capture-MS Mus musculus
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