Gene description for Atp6v0d1
Gene name ATPase, H+ transporting, lysosomal V0 subunit D1
Gene symbol Atp6v0d1
Other names/aliases AI267038
Ac39
Atp6d
P39
VATX
Vma6
Species Mus musculus
 Database cross references - Atp6v0d1
ExoCarta ExoCarta_11972
Entrez Gene 11972
UniProt P51863  
 Atp6v0d1 identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Atp6v0d1
Molecular Function
    hydrogen ion transmembrane transporter activity GO:0015078 IEA
    protein complex binding GO:0032403 ISO
    hydrogen-exporting ATPase activity, phosphorylative mechanism GO:0008553 IDA
Biological Process
    proton transport GO:0015992 IEA
    ATP hydrolysis coupled proton transport GO:0015991 IEA
    transport GO:0006810 IEA
    cell projection organization GO:0030030 IEA
    ion transport GO:0006811 IEA
    hydrogen ion transmembrane transport GO:1902600 IDA
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    protein complex GO:0043234 ISO
    vacuolar proton-transporting V-type ATPase complex GO:0016471 ISO
    centrosome GO:0005813 ISO
    synaptic vesicle GO:0008021 ISO
    proton-transporting V-type ATPase, V0 domain GO:0033179 IEA
    early endosome GO:0005769 IDA
    membrane GO:0016020 ISO
    lysosomal membrane GO:0005765 ISO
    apical plasma membrane GO:0016324 ISO
    axon terminus GO:0043679 ISO
    neuron projection GO:0043005 ISO
 Experiment description of studies that identified Atp6v0d1 in exosomes
1
Experiment ID 188
ISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Atp6v0d1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Atp6v0d1 is involved
PathwayEvidenceSource
Insulin receptor recycling IEA Reactome
Ion channel transport IEA Reactome
Transferrin endocytosis and recycling IEA Reactome





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