Gene description for Canx
Gene name calnexin
Gene symbol Canx
Other names/aliases 1110069N15Rik
AI988026
Cnx
D11Ertd153e
Species Mus musculus
 Database cross references - Canx
ExoCarta ExoCarta_12330
Entrez Gene 12330
UniProt P35564  
 Canx identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Canx
Molecular Function
    metal ion binding GO:0046872 IEA
    calcium ion binding GO:0005509 IEA
    carbohydrate binding GO:0030246 IEA
    poly(A) RNA binding GO:0044822 ISO
    ionotropic glutamate receptor binding GO:0035255 ISO
    glycoprotein binding GO:0001948 ISO
    protein binding GO:0005515 IPI
    apolipoprotein binding GO:0034185 ISO
    unfolded protein binding GO:0051082 ISO
Biological Process
    protein folding GO:0006457 IEA
    clathrin-mediated endocytosis GO:0072583 IMP
    chaperone-mediated protein folding GO:0061077 ISO
    synaptic vesicle endocytosis GO:0048488 IMP
Subcellular Localization
    ER-mitochondrion membrane contact site GO:0044233 ISO
    membrane GO:0016020 ISO
    rough endoplasmic reticulum GO:0005791 ISO
    cell GO:0005623 IMP
    axon GO:0030424 ISO
    neuronal cell body GO:0043025 ISO
    cytoplasm GO:0005737 ISO
    dendrite cytoplasm GO:0032839 ISO
    endoplasmic reticulum membrane GO:0005789 ISO
    dendritic spine GO:0043197 ISO
    smooth endoplasmic reticulum GO:0005790 ISO
    endoplasmic reticulum GO:0005783 ISO
    ribosome GO:0005840 ISO
    myelin sheath GO:0043209 IDA
    protein complex GO:0043234 ISO
    integral component of membrane GO:0016021 IDA
 Experiment description of studies that identified Canx in exosomes
1
Experiment ID 188
ISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Canx
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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