Gene description for Ifngr1
Gene name interferon gamma receptor 1
Gene symbol Ifngr1
Other names/aliases CD119
IFN-gammaR
Ifgr
Ifngr
Nktar
Species Mus musculus
 Database cross references - Ifngr1
ExoCarta ExoCarta_15979
Vesiclepedia VP_15979
Entrez Gene 15979
UniProt P15261  
 Ifngr1 identified in exosomes derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Ifngr1
Molecular Function
    cytokine binding GO:0019955 IEA
    cytokine receptor activity GO:0004896 IBA
Biological Process
    cytokine-mediated signaling pathway GO:0019221 IBA
Subcellular Localization
    postsynaptic density GO:0014069 ISO
    plasma membrane GO:0005886 IBA
    endoplasmic reticulum GO:0005783 ISO
    integral component of membrane GO:0016021 IBA
    vesicle GO:0031982 ISO
    membrane GO:0016020 IEA
    dendrite GO:0030425 ISO
 Experiment description of studies that identified Ifngr1 in exosomes
1
Experiment ID 907
MISEV standards
EM
EV Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
HSPA5
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
EM
EV Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
HSPA5
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Ifngr1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ifngr1 is involved
PathwayEvidenceSource
Interferon gamma signaling IEA Reactome
Regulation of IFNG signaling IEA Reactome





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