Gene description for Stmn1
Gene name stathmin 1
Gene symbol Stmn1
Other names/aliases 19k
Lag
Lap18
Op18
P18
P19
Pig
Pp17
Pp18
Pp19
Pr22
Smn
Species Mus musculus
 Database cross references - Stmn1
ExoCarta ExoCarta_16765
Entrez Gene 16765
UniProt P54227  
 Stmn1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Stmn1
Molecular Function
    protein binding GO:0005515 IPI
    tubulin binding GO:0015631 ISO
Biological Process
    mitotic spindle organization GO:0007052 ISO
    regulation of microtubule polymerization or depolymerization GO:0031110 IEA
    axonogenesis GO:0007409 IMP
    nervous system development GO:0007399 IEA
    positive regulation of cellular component movement GO:0051272 IGI
    negative regulation of microtubule polymerization GO:0031115 IDA
    cell differentiation GO:0030154 IEA
    multicellular organismal development GO:0007275 IEA
    neuron projection development GO:0031175 IBA
    microtubule depolymerization GO:0007019 ISO
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    cytoskeleton GO:0005856 IEA
    membrane GO:0016020 IDA
    intracellular GO:0005622 ISO
    microtubule GO:0005874 IEA
    cytosol GO:0005829 IDA
    cytoplasm GO:0005737 IDA
    neuron projection GO:0043005 IBA
 Experiment description of studies that identified Stmn1 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Stmn1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Stmn1 is involved
No pathways found





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