Gene description for Map1b
Gene name microtubule-associated protein 1B
Gene symbol Map1b
Other names/aliases A230055D22
AI843217
LC1
MAP5
Mtap-5
Mtap1b
Mtap5
Species Mus musculus
 Database cross references - Map1b
ExoCarta ExoCarta_17755
Entrez Gene 17755
UniProt P14873  
 Map1b identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Map1b
Molecular Function
    phospholipid binding GO:0005543 ISO
    protein complex binding GO:0032403 ISO
    protein binding GO:0005515 IPI
    cytoskeletal regulatory protein binding GO:0005519 TAS
    microtubule binding GO:0008017 ISO
    actin binding GO:0003779 ISO
Biological Process
    microtubule cytoskeleton organization GO:0000226 IEA
    microtubule-based process GO:0007017 TAS
    negative regulation of microtubule depolymerization GO:0007026 ISO
    negative regulation of intracellular transport GO:0032387 IMP
    mitochondrion transport along microtubule GO:0047497 IMP
    nervous system development GO:0007399 IEA
    establishment of monopolar cell polarity GO:0061162 IMP
    cellular process GO:0009987 ISO
    positive regulation of axon extension GO:0045773 ISO
    axonogenesis GO:0007409 IGI
    axon extension GO:0048675 IMP
    positive regulation of microtubule polymerization GO:0031116 ISO
    positive regulation of neuron differentiation GO:0045666 ISO
    microtubule bundle formation GO:0001578 ISO
    dendrite development GO:0016358 IMP
Subcellular Localization
    varicosity GO:0043196 ISO
    microtubule associated complex GO:0005875 TAS
    cytoplasm GO:0005737 ISO
    cell junction GO:0030054 IEA
    cell projection GO:0042995 IEA
    cytosol GO:0005829 IDA
    intracellular GO:0005622 IMP
    photoreceptor outer segment GO:0001750 IDA
    neuronal postsynaptic density GO:0097481 IDA
    microtubule GO:0005874 IEA
    growth cone GO:0030426 ISO
    dendrite GO:0030425 ISO
    perikaryon GO:0043204 ISO
    postsynaptic density GO:0014069 ISO
    plasma membrane GO:0005886 ISO
    cytoskeleton GO:0005856 ISO
    axon GO:0030424 ISO
    neuronal cell body GO:0043025 ISO
    perinuclear region of cytoplasm GO:0048471 ISO
    cell GO:0005623 IMP
    synapse GO:0045202 IEA
 Experiment description of studies that identified Map1b in exosomes
1
Experiment ID 188
ISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Map1b
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Map1b is involved
No pathways found





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