Gene description for APOBEC3A
Gene name apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
Gene symbol APOBEC3A
Other names/aliases A3A
ARP3
PHRBN
bK150C2.1
Species Homo sapiens
 Database cross references - APOBEC3A
ExoCarta ExoCarta_200315
Entrez Gene 200315
HGNC 17343
MIM 607109
UniProt P31941  
 APOBEC3A identified in exosomes derived from the following tissue/cell type
Keratinocytes 19530224    
Keratinocytes 19530224    
 Gene ontology annotations for APOBEC3A
Molecular Function
    deoxycytidine deaminase activity GO:0047844 IMP
    zinc ion binding GO:0008270 IEA
    protein binding GO:0005515 IPI
    cytidine deaminase activity GO:0004126 IMP
Biological Process
    DNA cytosine deamination GO:0070383 IMP
    cytidine deamination GO:0009972 IMP
    innate immune response GO:0045087 IDA
    negative regulation of viral genome replication GO:0045071 IDA
    defense response to virus GO:0051607 IDA
    DNA demethylation GO:0080111 IDA
    negative regulation of transposition GO:0010529 IDA
    cellular response to xenobiotic stimulus GO:0071466 IDA
    clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine GO:0044356 IDA
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    nucleus GO:0005634 IDA
    cytoplasm GO:0005737 IDA
 Experiment description of studies that identified APOBEC3A in exosomes
1
Experiment ID 189
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors Chavez-Muñoz C, Kilani RT, Ghahary A.
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Differentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 190
ISEV standards
EM
EV Biophysical techniques
HSC70
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors Chavez-Muñoz C, Kilani RT, Ghahary A.
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Undifferentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for APOBEC3A
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which APOBEC3A is involved
No pathways found





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