Gene description for Taldo1
Gene name transaldolase 1
Gene symbol Taldo1
Other names/aliases -
Species Mus musculus
 Database cross references - Taldo1
ExoCarta ExoCarta_21351
Vesiclepedia VP_21351
Entrez Gene 21351
UniProt Q93092  
 Taldo1 identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
Oligodendrocytes 21136642    
Pancreatic cells 19351151    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Taldo1
Molecular Function
    transaldolase activity GO:0004801 IBA
    transaldolase activity GO:0004801 IDA
    transaldolase activity GO:0004801 IMP
    transaldolase activity GO:0004801 ISO
    protein binding GO:0005515 IPI
    carbohydrate binding GO:0030246 ISO
    identical protein binding GO:0042802 IDA
    monosaccharide binding GO:0048029 ISO
Biological Process
    carbohydrate metabolic process GO:0005975 IEA
    fructose 6-phosphate metabolic process GO:0006002 ISO
    pentose-phosphate shunt GO:0006098 IDA
    pentose-phosphate shunt GO:0006098 IEA
    pentose-phosphate shunt GO:0006098 IMP
    pentose-phosphate shunt GO:0006098 ISO
    pentose-phosphate shunt, non-oxidative branch GO:0009052 IBA
    pentose-phosphate shunt, non-oxidative branch GO:0009052 ISO
    glyceraldehyde-3-phosphate metabolic process GO:0019682 ISO
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleus GO:0005634 IEA
    cytoplasm GO:0005737 IDA
    cytosol GO:0005829 IDA
 Experiment description of studies that identified Taldo1 in sEVs
1
Experiment ID 907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 33
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
Alix|TSG101
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21136642    
Organism Mus musculus
Experiment description Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?
Authors "Kramer-Albers EM, Bretz N, Tenzer S, Winterstein C, Mobius W, Berger H, Nave KA, Schild H, Trotter J"
Journal name PROTEOMICS_CL
Publication year 2007
Sample Oligodendrocytes
Sample name Oligodendrocytes
Oli-neu
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
Immunoelectron Microscopy
3
Experiment ID 188
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|UCHL1|HSP90
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors "Lee HS, Jeong J, Lee KJ."
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
4
Experiment ID 908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Taldo1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Nme2 18103
Co-fractionation Mus musculus
2 Atxn1  
Affinity Capture-MS Mus musculus
3 Sord  
Co-fractionation Mus musculus
4 Adss  
Co-fractionation Mus musculus
5 Hspe1 15528
Co-fractionation Mus musculus
6 Wdr1 22388
Co-fractionation Mus musculus
7 Thop1  
Co-fractionation Mus musculus
8 Fdps 110196
Co-fractionation Mus musculus
9 Kcnma1  
Affinity Capture-MS Mus musculus
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