Gene description for RNF152
Gene name ring finger protein 152
Gene symbol RNF152
Other names/aliases -
Species Homo sapiens
 Database cross references - RNF152
ExoCarta ExoCarta_220441
Entrez Gene 220441
HGNC 26811
UniProt Q8N8N0  
 RNF152 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for RNF152
Molecular Function
    ligase activity GO:0016874 IEA
    ubiquitin-protein transferase activity GO:0004842 IDA
    zinc ion binding GO:0008270 IEA
Biological Process
    apoptotic process GO:0006915 TAS
    protein K48-linked ubiquitination GO:0070936 IDA
Subcellular Localization
    lysosome GO:0005764 IDA
    lysosomal membrane GO:0005765 IEA
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified RNF152 in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for RNF152
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which RNF152 is involved
No pathways found





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