Gene description for GK2
Gene name glycerol kinase 2
Gene symbol GK2
Other names/aliases GKP2
GKTA
Species Homo sapiens
 Database cross references - GK2
ExoCarta ExoCarta_2712
Entrez Gene 2712
HGNC 4291
MIM 600148
UniProt Q14410  
 GK2 identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for GK2
Molecular Function
    glycerol kinase activity GO:0004370 NAS
    ATP binding GO:0005524 IEA
Biological Process
    glycerol-3-phosphate biosynthetic process GO:0046167 IBA
    glycerol metabolic process GO:0006071 IBA
    glycerol catabolic process GO:0019563 IEA
    triglyceride metabolic process GO:0006641 IBA
    phosphorylation GO:0016310 IBA
Subcellular Localization
    mitochondrial outer membrane GO:0005741 IEA
    cytoplasm GO:0005737 IBA
    extracellular exosome GO:0070062 IDA
    mitochondrion GO:0005739 IBA
 Experiment description of studies that identified GK2 in exosomes
1
Experiment ID 63
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✔
AQP2
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for GK2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which GK2 is involved
PathwayEvidenceSource
Triglyceride Biosynthesis TAS Reactome





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