Gene description for Gria2
Gene name	glutamate receptor, ionotropic, AMPA 2
Gene symbol	Gria2
Other names/aliases	GluA2 GluR-K2 GluR2 gluR-B
Species	Rattus norvegicus
Database cross references - Gria2
ExoCarta	ExoCarta_29627
Vesiclepedia	VP_29627
Entrez Gene	29627
UniProt	P19491
Gria2 identified in sEVs derived from the following tissue/cell type
Cortical neurones	16446100

Gene ontology annotations for Gria2

Molecular Function     SNARE binding GO:0000149 IPI     amyloid-beta binding GO:0001540 IPI     glutamate-gated receptor activity GO:0004970 IDA     glutamate-gated receptor activity GO:0004970 IEA     glutamate-gated receptor activity GO:0004970 ISO     glutamate-gated receptor activity GO:0004970 TAS     AMPA glutamate receptor activity GO:0004971 IBA     AMPA glutamate receptor activity GO:0004971 IDA     AMPA glutamate receptor activity GO:0004971 TAS     extracellular ligand-gated monoatomic ion channel activity GO:0005230 IDA     extracellularly glutamate-gated ion channel activity GO:0005234 ISO     protein binding GO:0005515 IPI     cytoskeletal protein binding GO:0008092 IPI     ligand-gated monoatomic ion channel activity GO:0015276 IEA     kainate selective glutamate receptor activity GO:0015277 IDA     immunoglobulin binding GO:0019865 IPI     protein kinase binding GO:0019901 IPI     glutamate-gated calcium ion channel activity GO:0022849 IDA     PDZ domain binding GO:0030165 IDA     PDZ domain binding GO:0030165 IPI     glutamate receptor binding GO:0035254 IPI     ionotropic glutamate receptor binding GO:0035255 IPI     signaling receptor activity GO:0038023 IDA     signaling receptor activity GO:0038023 IEA     identical protein binding GO:0042802 IPI     protein-containing complex binding GO:0044877 IPI     scaffold protein binding GO:0097110 IPI     ligand-gated monoatomic cation channel activity GO:0099094 IDA     ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential GO:0099507 IDA     ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential GO:0099507 IMP     ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential GO:0099507 NAS     transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential GO:1904315 IBA     transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential GO:1904315 IDA     transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential GO:1904315 IMP     transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential GO:1904315 ISO Biological Process     regulation of receptor recycling GO:0001919 IMP     chemical synaptic transmission GO:0007268 IDA     chemical synaptic transmission GO:0007268 ISO     response to lithium ion GO:0010226 IEP     calcium-mediated signaling GO:0019722 IEA     cerebral cortex development GO:0021987 IEP     receptor internalization GO:0031623 IDA     monoatomic ion transmembrane transport GO:0034220 IEA     ionotropic glutamate receptor signaling pathway GO:0035235 IEA     ionotropic glutamate receptor signaling pathway GO:0035235 ISO     ionotropic glutamate receptor signaling pathway GO:0035235 ISS     synaptic transmission, glutamatergic GO:0035249 IBA     establishment of protein localization GO:0045184 IMP     modulation of chemical synaptic transmission GO:0050804 IBA     positive regulation of synaptic transmission GO:0050806 IMP     protein tetramerization GO:0051262 IDA     regulation of synaptic transmission, glutamatergic GO:0051966 IMP     excitatory postsynaptic potential GO:0060079 IEA     response to fungicide GO:0060992 IEP     monoatomic cation transmembrane transport GO:0098655 IEA     regulation of presynaptic membrane potential GO:0099505 IEA     cellular response to glycine GO:1905430 IDA     cellular response to brain-derived neurotrophic factor stimulus GO:1990416 IDA Subcellular Localization     endoplasmic reticulum GO:0005783 ISO     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 ISO     plasma membrane GO:0005886 TAS     synaptic vesicle GO:0008021 ISO     ionotropic glutamate receptor complex GO:0008328 TAS     cell surface GO:0009986 IDA     postsynaptic density GO:0014069 IDA     postsynaptic density GO:0014069 ISO     membrane GO:0016020 ISO     axon GO:0030424 IDA     dendrite GO:0030425 IDA     dendrite GO:0030425 ISO     growth cone GO:0030426 IDA     synaptic vesicle membrane GO:0030672 IDA     synaptic vesicle membrane GO:0030672 ISO     asymmetric synapse GO:0032279 IDA     AMPA glutamate receptor complex GO:0032281 IBA     AMPA glutamate receptor complex GO:0032281 IDA     AMPA glutamate receptor complex GO:0032281 ISO     dendrite membrane GO:0032590 IDA     dendrite cytoplasm GO:0032839 IDA     protein-containing complex GO:0032991 IDA     protein-containing complex GO:0032991 IPI     somatodendritic compartment GO:0036477 ISO     presynaptic membrane GO:0042734 IDA     presynaptic membrane GO:0042734 IDA     neuron projection GO:0043005 ISO     neuronal cell body GO:0043025 IDA     terminal bouton GO:0043195 IDA     dendritic spine GO:0043197 IBA     dendritic spine GO:0043197 IDA     dendritic shaft GO:0043198 IDA     perikaryon GO:0043204 IDA     dendritic spine neck GO:0044326 IDA     dendritic spine head GO:0044327 IDA     synapse GO:0045202 IDA     synapse GO:0045202 ISO     postsynaptic membrane GO:0045211 IDA     postsynaptic membrane GO:0045211 ISO     presynaptic active zone membrane GO:0048787 IDA     synaptic membrane GO:0097060 ISO     Schaffer collateral - CA1 synapse GO:0098685 IDA     Schaffer collateral - CA1 synapse GO:0098685 IMP     Schaffer collateral - CA1 synapse GO:0098685 ISO     presynapse GO:0098793 IDA     postsynaptic density membrane GO:0098839 IBA     postsynaptic density membrane GO:0098839 IDA     postsynaptic density membrane GO:0098839 IEA     postsynaptic density membrane GO:0098839 ISO     postsynaptic density membrane GO:0098839 ISO     glutamatergic synapse GO:0098978 IDA     glutamatergic synapse GO:0098978 ISO     perisynaptic space GO:0099544 ISO     spine synapse GO:0106033 IDA