Gene description for Igf2bp2
Gene name insulin-like growth factor 2 mRNA binding protein 2
Gene symbol Igf2bp2
Other names/aliases C330012H03Rik
IMP-2
Imp2
Neilsen
Species Mus musculus
 Database cross references - Igf2bp2
ExoCarta ExoCarta_319765
Entrez Gene 319765
UniProt Q5SF07  
 Igf2bp2 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Igf2bp2
Molecular Function
    mRNA 5'-UTR binding GO:0048027 ISO
    mRNA binding GO:0003729 IEA
    mRNA 3'-UTR binding GO:0003730 ISO
    nucleic acid binding GO:0003676 IEA
    nucleotide binding GO:0000166 IEA
    RNA binding GO:0003723 IEA
    poly(A) RNA binding GO:0044822 ISO
Biological Process
    regulation of translation GO:0006417 IEA
    transport GO:0006810 IEA
    mRNA transport GO:0051028 IEA
Subcellular Localization
    cytoplasm GO:0005737 ISO
    nucleus GO:0005634 ISO
    cytoskeleton GO:0005856 ISO
 Experiment description of studies that identified Igf2bp2 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Igf2bp2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Igf2bp2 is involved
No pathways found





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