Gene description for Pgk
Gene name Phosphoglycerate kinase
Gene symbol Pgk
Other names/aliases 169C9S
CG3127
DmelCG3127
ESTS:169C9S
PGK
anon-sts18
l(2)23AB3
l(2)23Ac
pgk
Species Drosophila melanogaster
 Database cross references - Pgk
ExoCarta ExoCarta_33461
Vesiclepedia VP_33461
Entrez Gene 33461
UniProt Q01604  
 Pgk identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Pgk
Biological Process
    chemical synaptic transmission GO:0007268 IDA
    muscle cell cellular homeostasis GO:0046716 IGI
    canonical glycolysis GO:0061621 IMP
Subcellular Localization
    Z disc GO:0030018 IDA
    M band GO:0031430 IDA
 Experiment description of studies that identified Pgk in exosomes
1
Experiment ID 202
MISEV standards
✔
IEM
Biophysical techniques
✔
TSG10|RAB35|FLOT2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors "Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP."
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Pgk
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Gpdh  
Affinity Capture-MS Drosophila melanogaster
2 awd  
Affinity Capture-MS Drosophila melanogaster
3 CG14715  
Affinity Capture-MS Drosophila melanogaster
4 Yp2  
Affinity Capture-MS Drosophila melanogaster
5 CG7430  
Affinity Capture-MS Drosophila melanogaster
6 CG31343  
Affinity Capture-MS Drosophila melanogaster
7 CG16826  
Affinity Capture-MS Drosophila melanogaster
8 Sec5  
Two-hybrid Drosophila melanogaster
9 CG5500  
Affinity Capture-MS Drosophila melanogaster
10 Sh3beta 38820
Affinity Capture-MS Drosophila melanogaster
11 CG32473  
Affinity Capture-MS Drosophila melanogaster
12 Argk  
Affinity Capture-MS Drosophila melanogaster
13 Uch 33397
Affinity Capture-MS Drosophila melanogaster
14 Adh  
Affinity Capture-MS Drosophila melanogaster
15 TER94  
Affinity Capture-MS Drosophila melanogaster
16 Ald  
Affinity Capture-MS Drosophila melanogaster
17 CG5506  
Affinity Capture-MS Drosophila melanogaster
18 Lsp2  
Affinity Capture-MS Drosophila melanogaster
19 CG10638  
Affinity Capture-MS Drosophila melanogaster
20 regucalcin  
Affinity Capture-MS Drosophila melanogaster
21 Scp1  
Affinity Capture-MS Drosophila melanogaster
22 Mdh2  
Affinity Capture-MS Drosophila melanogaster
23 Pglym78  
Affinity Capture-MS Drosophila melanogaster
24 scu  
Affinity Capture-MS Drosophila melanogaster
25 Eno  
Affinity Capture-MS Drosophila melanogaster
26 Hop 33202
Affinity Capture-MS Drosophila melanogaster
27 CG4598  
Affinity Capture-MS Drosophila melanogaster
28 CTPsyn  
Proximity Label-MS Drosophila melanogaster
29 Fkbp14  
Affinity Capture-MS Drosophila melanogaster
30 chic  
Affinity Capture-MS Drosophila melanogaster
31 AnxB10  
Affinity Capture-MS Drosophila melanogaster
32 PHGPx 38413
Affinity Capture-MS Drosophila melanogaster
33 GlyP  
Affinity Capture-MS Drosophila melanogaster
34 Moe  
Affinity Capture-MS Drosophila melanogaster
35 Prx2540-2 36098
Affinity Capture-MS Drosophila melanogaster
36 ftz-f1  
Affinity Capture-MS Drosophila melanogaster
37 Gapdh2  
Affinity Capture-MS Drosophila melanogaster
View the network image/svg+xml
 Pathways in which Pgk is involved
PathwayEvidenceSource
Gluconeogenesis IEA Reactome
Glucose metabolism IEA Reactome
Glycolysis IEA Reactome
Metabolism IEA Reactome
Metabolism of carbohydrates IEA Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here