Gene description for PHGPx
Gene name CG12013 gene product from transcript CG12013-RC
Gene symbol PHGPx
Other names/aliases CG12013
DmGPx
DmPHGPx
DmelCG12013
GPx
GTPx
GTPx-1
Gtpx-1
PGTPx
anon-WO0257455.17
Species Drosophila melanogaster
 Database cross references - PHGPx
ExoCarta ExoCarta_38413
Entrez Gene 38413
 PHGPx identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for PHGPx
Molecular Function
    peroxidase activity GO:0004601 IDA
    glutathione peroxidase activity GO:0004602 ISS
Biological Process
    oxidation-reduction process GO:0055114 IEA
    response to lipid hydroperoxide GO:0006982 ISS
    response to oxidative stress GO:0006979 IMP
Subcellular Localization
    endomembrane system GO:0012505 IDA
    mitochondrion GO:0005739 ISS
    cytoplasm GO:0005737 ISS
    Golgi apparatus GO:0005794 IDA
 Experiment description of studies that identified PHGPx in exosomes
1
Experiment ID 202
ISEV standards
IEM
EV Biophysical techniques
TSG10|RAB35
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PHGPx
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PHGPx is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here