Gene description for Hop
Gene name Hsp70/Hsp90 organizing protein homolog
Gene symbol Hop
Other names/aliases CG2720
DmelCG2720
EP(2)0418
HOP
Sti1
dHop
dSTI1
dhop
dmSTI1
hop
l(2)k00616
Species Drosophila melanogaster
 Database cross references - Hop
ExoCarta ExoCarta_33202
Entrez Gene 33202
 Hop identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Hop
Molecular Function
    unfolded protein binding GO:0051082 ISS
Biological Process
    protein folding GO:0006457 ISS
 Experiment description of studies that identified Hop in exosomes
1
Experiment ID 202
ISEV standards
IEM
EV Biophysical techniques
TSG10|RAB35
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Hop
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Hop is involved
No pathways found





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