Gene description for Hop
Gene name Hsp70/Hsp90 organizing protein homolog
Gene symbol Hop
Other names/aliases CG2720
DmelCG2720
EP(2)0418
HOP
Sti1
dHop
dSTI1
dhop
dmSTI1
hop
l(2)k00616
Species Drosophila melanogaster
 Database cross references - Hop
ExoCarta ExoCarta_33202
Vesiclepedia VP_33202
Entrez Gene 33202
 Hop identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Hop
Biological Process
    multivesicular body fusion to apical plasma membrane GO:0098866 IMP
 Experiment description of studies that identified Hop in exosomes
1
Experiment ID 202
MISEV standards
IEM
Biophysical techniques
TSG10|RAB35|FLOT2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors "Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP."
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Hop
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HmgD  
Affinity Capture-MS Drosophila melanogaster
2 awd  
Affinity Capture-MS Drosophila melanogaster
3 CG10638  
Affinity Capture-MS Drosophila melanogaster
4 CG16817 41173
Affinity Capture-MS Drosophila melanogaster
5 Fim 32721
Affinity Capture-MS Drosophila melanogaster
6 Df31  
Affinity Capture-MS Drosophila melanogaster
7 TER94  
Affinity Capture-MS Drosophila melanogaster
8 Nlp  
Affinity Capture-MS Drosophila melanogaster
9 zuc  
Proximity Label-MS Drosophila melanogaster
10 smt3  
Affinity Capture-MS Drosophila melanogaster
11 CG7911  
Affinity Capture-MS Drosophila melanogaster
12 Pgk 33461
Affinity Capture-MS Drosophila melanogaster
13 Crc  
Affinity Capture-MS Drosophila melanogaster
14 Aldh-III  
Two-hybrid Drosophila melanogaster
15 EndoGI 34953
Affinity Capture-MS Drosophila melanogaster
16 Nelf-E  
Affinity Capture-MS Drosophila melanogaster
17 Eb1  
Affinity Capture-MS Drosophila melanogaster
18 Uch 33397
Affinity Capture-MS Drosophila melanogaster
19 CG11267  
Affinity Capture-MS Drosophila melanogaster
20 GstO3 38972
Affinity Capture-MS Drosophila melanogaster
21 Nup133  
Two-hybrid Drosophila melanogaster
22 CG2862  
Affinity Capture-MS Drosophila melanogaster
23 eIF-5A  
Affinity Capture-MS Drosophila melanogaster
24 GstE6  
Affinity Capture-MS Drosophila melanogaster
25 regucalcin  
Affinity Capture-MS Drosophila melanogaster
26 CG2852  
Affinity Capture-MS Drosophila melanogaster
27 CG9117  
Two-hybrid Drosophila melanogaster
28 Mdh2  
Affinity Capture-MS Drosophila melanogaster
29 scu  
Affinity Capture-MS Drosophila melanogaster
30 scf  
Affinity Capture-MS Drosophila melanogaster
31 Bacc  
Affinity Capture-MS Drosophila melanogaster
32 Tudor-SN 38045
Affinity Capture-MS Drosophila melanogaster
33 Eno  
Affinity Capture-MS Drosophila melanogaster
34 yip2  
Affinity Capture-MS Drosophila melanogaster
35 cib 31359
Affinity Capture-MS Drosophila melanogaster
36 Pdi  
Affinity Capture-MS Drosophila melanogaster
37 Sh3beta 38820
Affinity Capture-MS Drosophila melanogaster
38 CG6084  
Affinity Capture-MS Drosophila melanogaster
39 chic  
Affinity Capture-MS Drosophila melanogaster
40 eEF1delta  
Affinity Capture-MS Drosophila melanogaster
41 Hsp83  
Two-hybrid Drosophila melanogaster
42 Akap200  
Affinity Capture-MS Drosophila melanogaster
43 AnxB10  
Affinity Capture-MS Drosophila melanogaster
44 CG8036 41027
Affinity Capture-MS Drosophila melanogaster
45 PHGPx 38413
Affinity Capture-MS Drosophila melanogaster
46 Chd64  
Affinity Capture-MS Drosophila melanogaster
47 Nacalpha  
Affinity Capture-MS Drosophila melanogaster
48 Moe  
Affinity Capture-MS Drosophila melanogaster
49 FK506-bp2  
Affinity Capture-MS Drosophila melanogaster
50 Prx2540-2 36098
Affinity Capture-MS Drosophila melanogaster
51 Hsc70Cb 39557
Affinity Capture-MS Drosophila melanogaster
52 Gdi 34264
Affinity Capture-MS Drosophila melanogaster
View the network image/svg+xml
 Pathways in which Hop is involved
No pathways found





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