Gene description for Gdi
Gene name GDP dissociation inhibitor
Gene symbol Gdi
Other names/aliases CG4422
DmelCG4422
GDI
GdI
N7-3
dGDI
l(2)N7-3
lincRNA.S746
rab GDI
Species Drosophila melanogaster
 Database cross references - Gdi
ExoCarta ExoCarta_34264
Vesiclepedia VP_34264
Entrez Gene 34264
 Gdi identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Gdi
Molecular Function
    GDP-dissociation inhibitor activity GO:0005092 IDA
Biological Process
    neurotransmitter secretion GO:0007269 NAS
    vesicle-mediated transport GO:0016192 NAS
Subcellular Localization
    cytosol GO:0005829 HDA
    synaptic vesicle GO:0008021 NAS
 Experiment description of studies that identified Gdi in exosomes
1
Experiment ID 202
MISEV standards
IEM
Biophysical techniques
TSG10|RAB35|FLOT2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors "Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP."
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Gdi
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CG7787  
Affinity Capture-MS Drosophila melanogaster
2 Rab5 33418
Affinity Capture-MS Drosophila melanogaster
3 CG10638  
Affinity Capture-MS Drosophila melanogaster
4 RpL38  
Affinity Capture-MS Drosophila melanogaster
5 Rab35  
Affinity Capture-MS Drosophila melanogaster
Affinity Capture-MS Drosophila melanogaster
6 Uch 33397
Affinity Capture-MS Drosophila melanogaster
7 GstO3 38972
Affinity Capture-MS Drosophila melanogaster
8 GstE6  
Affinity Capture-MS Drosophila melanogaster
9 CG14894  
Proximity Label-MS Drosophila melanogaster
10 regucalcin  
Affinity Capture-MS Drosophila melanogaster
11 Rab10  
Affinity Capture-MS Drosophila melanogaster
12 Rab11 42501
Affinity Capture-MS Drosophila melanogaster
13 Mdh2  
Affinity Capture-MS Drosophila melanogaster
14 Rab7  
Affinity Capture-MS Drosophila melanogaster
15 Eno  
Affinity Capture-MS Drosophila melanogaster
16 Hop 33202
Affinity Capture-MS Drosophila melanogaster
17 CG6412  
Two-hybrid Drosophila melanogaster
18 CTPsyn  
Proximity Label-MS Drosophila melanogaster
19 yip2  
Affinity Capture-MS Drosophila melanogaster
20 EndoGI 34953
Affinity Capture-MS Drosophila melanogaster
21 CG6084  
Affinity Capture-MS Drosophila melanogaster
22 Akap200  
Affinity Capture-MS Drosophila melanogaster
23 AnxB10  
Affinity Capture-MS Drosophila melanogaster
24 Rab3  
Affinity Capture-MS Drosophila melanogaster
25 Moe  
Affinity Capture-MS Drosophila melanogaster
26 Prx2540-2 36098
Affinity Capture-MS Drosophila melanogaster
27 Hsc70Cb 39557
Affinity Capture-MS Drosophila melanogaster
View the network image/svg+xml
 Pathways in which Gdi is involved
No pathways found





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