Gene description for Hsc70Cb
Gene name CG6603 gene product from transcript CG6603-RI
Gene symbol Hsc70Cb
Other names/aliases 0041/12
0318/20
1342/17
1348/02
1485/13
BEST:LD32772
CG6603
DmelCG6603
HSC-70
HSC70
HSC70cb
HSP110
HSP110-1
Hsc70
LD32772
anon-WO0118547.302
dHsp110
hsc70Cb
hsc70cb
l(3)00082
l(3)07621
l(3)134217
l(3)148513
l(3)70Ca
l(3)70Cb
l(3)S134217
l(3)S134802
l(3)S148513
Species Drosophila melanogaster
 Database cross references - Hsc70Cb
ExoCarta ExoCarta_39557
Entrez Gene 39557
 Hsc70Cb identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Hsc70Cb
Molecular Function
    chaperone binding GO:0051087 ISS
Biological Process
    protein folding GO:0006457 ISS
Subcellular Localization
    cytosol GO:0005829 IDA
    cytoplasm GO:0005737 IDA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified Hsc70Cb in exosomes
1
Experiment ID 202
ISEV standards
IEM
EV Biophysical techniques
TSG10|RAB35
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Hsc70Cb
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Hsc70Cb is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here