Gene description for EndoGI
Gene name Endonuclease G inhibitor
Gene symbol EndoGI
Other names/aliases BG:DS07473.2
CG4930
DmelCG4930
dEndoGI
endoGI
Species Drosophila melanogaster
 Database cross references - EndoGI
ExoCarta ExoCarta_34953
Vesiclepedia VP_34953
Entrez Gene 34953
 EndoGI identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for EndoGI
Molecular Function
    ribonuclease inhibitor activity GO:0008428 IDA
Biological Process
    positive regulation of Notch signaling pathway GO:0045747 IMP
Subcellular Localization
    nucleus GO:0005634 IDA
 Experiment description of studies that identified EndoGI in exosomes
1
Experiment ID 202
MISEV standards
IEM
Biophysical techniques
TSG10|RAB35|FLOT2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors "Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP."
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for EndoGI
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CG14715  
Affinity Capture-MS Drosophila melanogaster
2 Inos 35671
Affinity Capture-MS Drosophila melanogaster
3 awd  
Affinity Capture-MS Drosophila melanogaster
4 CG10638  
Affinity Capture-MS Drosophila melanogaster
5 Sh3beta 38820
Affinity Capture-MS Drosophila melanogaster
6 CG10157  
Two-hybrid Drosophila melanogaster
7 Nlp  
Affinity Capture-MS Drosophila melanogaster
8 CG1707  
Affinity Capture-MS Drosophila melanogaster
9 CG14062  
Affinity Capture-MS Drosophila melanogaster
10 PHGPx 38413
Affinity Capture-MS Drosophila melanogaster
11 Crc  
Affinity Capture-MS Drosophila melanogaster
12 lms  
Two-hybrid Drosophila melanogaster
13 Uch 33397
Affinity Capture-MS Drosophila melanogaster
14 GstO3 38972
Affinity Capture-MS Drosophila melanogaster
15 CG2862  
Affinity Capture-MS Drosophila melanogaster
16 CG17778  
Two-hybrid Drosophila melanogaster
17 Iap2  
Affinity Capture-MS Drosophila melanogaster
18 regucalcin  
Affinity Capture-MS Drosophila melanogaster
19 CG2852  
Affinity Capture-MS Drosophila melanogaster
20 Mdh2  
Affinity Capture-MS Drosophila melanogaster
21 scu  
Affinity Capture-MS Drosophila melanogaster
22 scf  
Affinity Capture-MS Drosophila melanogaster
23 CG6709  
Two-hybrid Drosophila melanogaster
24 CG5174 37117
Affinity Capture-MS Drosophila melanogaster
25 flr 39505
Affinity Capture-MS Drosophila melanogaster
26 Eno  
Affinity Capture-MS Drosophila melanogaster
27 Hop 33202
Affinity Capture-MS Drosophila melanogaster
28 Fkbp14  
Affinity Capture-MS Drosophila melanogaster
29 EndoG  
Affinity Capture-MS Drosophila melanogaster
30 sel  
Affinity Capture-MS Drosophila melanogaster
31 CG10863  
Affinity Capture-MS Drosophila melanogaster
32 yip2  
Affinity Capture-MS Drosophila melanogaster
33 cib 31359
Affinity Capture-MS Drosophila melanogaster
34 Ald  
Affinity Capture-MS Drosophila melanogaster
35 AnxB10  
Affinity Capture-MS Drosophila melanogaster
36 ade5  
Two-hybrid Drosophila melanogaster
37 Nacalpha  
Affinity Capture-MS Drosophila melanogaster
38 Moe  
Affinity Capture-MS Drosophila melanogaster
39 CG6084  
Affinity Capture-MS Drosophila melanogaster
40 Prx2540-2 36098
Affinity Capture-MS Drosophila melanogaster
41 Pgd 31185
Affinity Capture-MS Drosophila melanogaster
42 Hsc70Cb 39557
Affinity Capture-MS Drosophila melanogaster
43 Gdi 34264
Affinity Capture-MS Drosophila melanogaster
View the network image/svg+xml
 Pathways in which EndoGI is involved
No pathways found





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