Gene description for Fim
Gene name Fimbrin
Gene symbol Fim
Other names/aliases CG8649
DmelCG8649
FIM
fim
Species Drosophila melanogaster
 Database cross references - Fim
ExoCarta ExoCarta_32721
Entrez Gene 32721
 Fim identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Fim
Molecular Function
    actin binding GO:0003779 NAS
    calcium ion binding GO:0005509 IEA
Biological Process
    female meiosis chromosome segregation GO:0016321 IMP
Subcellular Localization
    cytosol GO:0005829 IDA
    contractile ring GO:0070938 IDA
    apical cortex GO:0045179 IDA
 Experiment description of studies that identified Fim in exosomes
1
Experiment ID 202
ISEV standards
IEM
EV Biophysical techniques
TSG10|RAB35
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Fim
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Fim is involved
No pathways found





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