Gene description for Fim
Gene name Fimbrin
Gene symbol Fim
Other names/aliases CG8649
DmelCG8649
FIM
fim
Species Drosophila melanogaster
 Database cross references - Fim
ExoCarta ExoCarta_32721
Vesiclepedia VP_32721
Entrez Gene 32721
 Fim identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Fim
Biological Process
    cortical actin cytoskeleton organization GO:0030866 IGI
    actin crosslink formation GO:0051764 IMP
    syncytial embryo cellularization GO:0110069 IMP
Subcellular Localization
    cytosol GO:0005829 HDA
    apical cortex GO:0045179 HDA
    contractile ring GO:0070938 HDA
 Experiment description of studies that identified Fim in exosomes
1
Experiment ID 202
MISEV standards
IEM
Biophysical techniques
TSG10|RAB35|FLOT2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors "Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP."
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Fim
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Inos 35671
Affinity Capture-MS Drosophila melanogaster
2 GstE6  
Affinity Capture-MS Drosophila melanogaster
3 boca  
Affinity Capture-MS Drosophila melanogaster
4 Df31  
Affinity Capture-MS Drosophila melanogaster
5 Lamp1  
Affinity Capture-MS Drosophila melanogaster
6 CG13887  
Affinity Capture-MS Drosophila melanogaster
7 Nlp  
Affinity Capture-MS Drosophila melanogaster
8 CG11267  
Affinity Capture-MS Drosophila melanogaster
9 Crc  
Affinity Capture-MS Drosophila melanogaster
10 Tcp-1eta 41054
Affinity Capture-MS Drosophila melanogaster
11 Chd64  
Affinity Capture-MS Drosophila melanogaster
12 c(3)G  
Two-hybrid Drosophila melanogaster
13 Eb1  
Affinity Capture-MS Drosophila melanogaster
14 Uch 33397
Affinity Capture-MS Drosophila melanogaster
15 Pi3K68D  
Affinity Capture-MS Drosophila melanogaster
16 GstO3 38972
Affinity Capture-MS Drosophila melanogaster
17 CG10638  
Affinity Capture-MS Drosophila melanogaster
18 CG8036 41027
Affinity Capture-MS Drosophila melanogaster
19 CG17337  
Affinity Capture-MS Drosophila melanogaster
20 Glt  
Affinity Capture-MS Drosophila melanogaster
21 Gp93  
Affinity Capture-MS Drosophila melanogaster
22 scu  
Affinity Capture-MS Drosophila melanogaster
23 scf  
Affinity Capture-MS Drosophila melanogaster
24 CG17162  
Two-hybrid Drosophila melanogaster
25 Men 47173
Affinity Capture-MS Drosophila melanogaster
26 Hop 33202
Affinity Capture-MS Drosophila melanogaster
27 OstDelta  
Affinity Capture-MS Drosophila melanogaster
28 CTPsyn  
Proximity Label-MS Drosophila melanogaster
29 PCNA  
Affinity Capture-MS Drosophila melanogaster
30 Pdi  
Affinity Capture-MS Drosophila melanogaster
31 CG16817 41173
Affinity Capture-MS Drosophila melanogaster
32 fax  
Affinity Capture-MS Drosophila melanogaster
33 eEF1delta  
Affinity Capture-MS Drosophila melanogaster
34 Sh3beta 38820
Affinity Capture-MS Drosophila melanogaster
35 Akap200  
Affinity Capture-MS Drosophila melanogaster
36 AnxB10  
Affinity Capture-MS Drosophila melanogaster
37 TER94  
Affinity Capture-MS Drosophila melanogaster
38 Nacalpha  
Affinity Capture-MS Drosophila melanogaster
39 CG9467  
Affinity Capture-MS Drosophila melanogaster
40 Moe  
Affinity Capture-MS Drosophila melanogaster
41 Prx2540-2 36098
Affinity Capture-MS Drosophila melanogaster
42 RpLP0  
Affinity Capture-MS Drosophila melanogaster
View the network image/svg+xml
 Pathways in which Fim is involved
No pathways found





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